Sucralfate
sucrose octasulfate - aluminum complex
CAS: 54182-58-0
Molecular Formula: C12H14O35S8
Sucralfate - Names and Identifiers
| Name | sucrose octasulfate - aluminum complex |
| Synonyms | aluminum Sucralfate trihydrate Sucrose octasulfate Caluminum complex sucrose octasulfate - aluminum complex [(2R,3S,4S,5R)-4,5-disulfonatooxy-2-(sulfonatooxymethyl)-2-[(2S,3R,4S,5R,6R)-3,4,5-trisulfonatooxy-6-(sulfonatooxymethyl)tetrahydropyran-2-yl]oxy-tetrahydrofuran-3-yl] sulfate |
| CAS | 54182-58-0 |
| EINECS | 259-018-4 |
| InChI | InChI=1/C12H22O35S8/c13-48(14,15)37-1-4-6(43-51(22,23)24)8(45-53(28,29)30)9(46-54(31,32)33)11(40-4)42-12(3-39-50(19,20)21)10(47-55(34,35)36)7(44-52(25,26)27)5(41-12)2-38-49(16,17)18/h4-11H,1-3H2,(H,13,14,15)(H,16,17,18)(H,19,20,21)(H,22,23,24)(H,25,26,27)(H,28,29,30)(H,31,32,33)(H,34,35,36)/p-8/t4-,5-,6-,7-,8+,9-,10+,11-,12+/m1/s1 |
Sucralfate - Physico-chemical Properties
| Molecular Formula | C12H14O35S8 |
| Molar Mass | 974.743 |
| Melting Point | >220°C (dec.) |
| Solubility | Practically insoluble in water, in ethanol (96 per cent) and in methylene chloride. It dissolves in dilute solutions of mineral acids and alkali hydroxides. |
| Appearance | neat |
| Color | White |
| pKa | pKa = 0.43 to 1.19(at 25℃) |
| Storage Condition | Inert atmosphere,2-8°C |
| Physical and Chemical Properties | Sucralfate is a white amorphous powder, odorless, almost tasteless, and hygroscopic. Dissolved in dilute hydrochloric acid and sodium hydroxide, almost insoluble in water, ethanol and chloroform. |
| Use | For the treatment of gastric ulcer and duodenal ulcer, acid and inhibit the role of Pepsin |
| In vitro study | Sucralfate may interfere with the adhesion of intestinal epithelial cells to collagen I through the steric effect, thereby inhibiting the motility of intestinal epithelial cells. It protects RGMl cells from acid and pepsin. |
| In vivo study | The protective effect of Sucralfate against acute radiation-induced colitis may be achieved by inhibiting radiation-induced apoptosis via p53 and protecting colonic epithelial stem cells. |
Sucralfate - Risk and Safety
| WGK Germany | 2 |
| RTECS | BD0900000 |
| HS Code | 29400090 |
Sucralfate - Upstream Downstream Industry
| Raw Materials | Pyridine Sodium hydroxide Sulfur trioxide Sucrose |
Sucralfate - Introduction
sucrose octasulfate-aluminum complex is a compound whose chemical formula is (C12H24O11)8 · xAl(III), where x represents that the amount of aluminum can vary. The following is a description of the nature, use, preparation and safety information of sucrose octasulfate-aluminum complex:
Nature:
1. appearance: sucrose octasulfate-aluminum complex is a white to light yellow powder.
2. solubility: sucrose octasulfate-aluminum complex has low solubility in water.
3. Stability: sucrose octasulfate-aluminum complex has good stability and can maintain its structure under acidic conditions.
Use:
1. anti-inflammatory effect: sucrose octasulfate-aluminum complex can be used to treat inflammation and trauma, reduce the associated pain and redness.
2. Promote healing: sucrose octasulfate-aluminum complex can accelerate the healing process of wounds and help repair wounds.
3. Anti-infection: sucrose octasulfate-aluminum complex has antibacterial and antiviral effects and can be used to prevent and treat some infectious diseases.
Preparation Method:
The preparation method of sucrose octasulfate-aluminum complex is relatively complicated, and is generally obtained by reacting sulfur sugar and aluminum salt under appropriate conditions. The specific preparation method may be specifically adjusted as required.
Safety Information:
1. skin and eye irritation: sucrose octasulfate-aluminum complex may be irritating to the skin and eyes, and attention should be paid to avoid contact when using.
2. Toxicity: At present, the toxicity information of sucrose octasulfate-aluminum complex is limited, but relevant safety procedures should be followed when using.
3. storage note: sucrose octasulfate-aluminum complex should be stored in a dry, cool place, avoid contact with oxidants or flammable substances.
Nature:
1. appearance: sucrose octasulfate-aluminum complex is a white to light yellow powder.
2. solubility: sucrose octasulfate-aluminum complex has low solubility in water.
3. Stability: sucrose octasulfate-aluminum complex has good stability and can maintain its structure under acidic conditions.
Use:
1. anti-inflammatory effect: sucrose octasulfate-aluminum complex can be used to treat inflammation and trauma, reduce the associated pain and redness.
2. Promote healing: sucrose octasulfate-aluminum complex can accelerate the healing process of wounds and help repair wounds.
3. Anti-infection: sucrose octasulfate-aluminum complex has antibacterial and antiviral effects and can be used to prevent and treat some infectious diseases.
Preparation Method:
The preparation method of sucrose octasulfate-aluminum complex is relatively complicated, and is generally obtained by reacting sulfur sugar and aluminum salt under appropriate conditions. The specific preparation method may be specifically adjusted as required.
Safety Information:
1. skin and eye irritation: sucrose octasulfate-aluminum complex may be irritating to the skin and eyes, and attention should be paid to avoid contact when using.
2. Toxicity: At present, the toxicity information of sucrose octasulfate-aluminum complex is limited, but relevant safety procedures should be followed when using.
3. storage note: sucrose octasulfate-aluminum complex should be stored in a dry, cool place, avoid contact with oxidants or flammable substances.
Last Update：2024-04-10 22:29:15
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View History
Sucralfate
Ibuprofen Related CoMpound (1,3-Dihydroxyprop-2-yl 2-(4-Isobutylphenyl)Propanonate)
2-(环己基甲基)苯酚
吡唑-3-卡巴肼,4-溴-1-甲基-
6-溴-1H-吲哚-2-羧酸叔丁酯
tcnqf4 (organic electronic material)
PTC299
1-BOC-3-氟哌啶-3-甲酸甲酯
2-(Chloromethyl)-6-methoxypyridine hydrochloride
4-甲基-5-(环氧乙烷-2-基)异苯并呋喃-1(3H)-酮
Ibuprofen Related CoMpound (1,3-Dihydroxyprop-2-yl 2-(4-Isobutylphenyl)Propanonate)
2-(环己基甲基)苯酚
吡唑-3-卡巴肼,4-溴-1-甲基-
6-溴-1H-吲哚-2-羧酸叔丁酯
tcnqf4 (organic electronic material)
PTC299
1-BOC-3-氟哌啶-3-甲酸甲酯
2-(Chloromethyl)-6-methoxypyridine hydrochloride
4-甲基-5-(环氧乙烷-2-基)异苯并呋喃-1(3H)-酮
Raw Materials for Sucralfate