CEFADROXILMONOHYDRATE
Cefadroxil
CAS: 66592-87-8
Molecular Formula: C16H19N3O6S
CEFADROXILMONOHYDRATE - Names and Identifiers
CEFADROXILMONOHYDRATE - Physico-chemical Properties
| Molecular Formula | C16H19N3O6S |
| Molar Mass | 381.4 |
| Melting Point | 197 °C |
| Storage Condition | 2-8 ℃, dark |
| Physical and Chemical Properties | It is white or off-white crystalline powder with specific odor. Slightly soluble in water, almost insoluble in ethanol, ether or chloroform. |
| Use | Uses for Staphylococcus, Streptococcus, Pneumonia coccus, Escherichia coli and other causes of urinary system, respiratory tract, skin, facial features and gastrointestinal tract infection treatment |
CEFADROXILMONOHYDRATE - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R42/43 - May cause sensitization by inhalation and skin contact. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S36/37 - Wear suitable protective clothing and gloves. |
CEFADROXILMONOHYDRATE - Synthesis of cefadroxil catalyzed by Immobilized enzyme
from VIP Journal Professional Edition
Author:
Mei Jianfeng , Wang p , Wang Min , Yang Gensheng
Abstract:
with 7-amino-3-deacetoxycephalosporanic acid (7-ADCA) as the mother nucleus and p-hydroxyphenylglycine methyl ester (HPGME) as the acyl donor, in the phosphate buffer system, synthesis of cefadroxil catalyzed by immobilized penicillin acylase. Through the investigation of the influencing factors in the enzymatic synthesis of cefadroxil, the better synthesis conditions were selected. The results showed that the reaction temperature was 25 C, the reaction system pH 6.5,7-ADCA,HPGME and Immobilized enzyme dosage were 2.5%,7.5%,1.5%, the conversion of the synthetic reaction can reach 80.3%.
Key words:
cefadroxil; Enzymatic synthesis; penicillin acylase
DOI:
10.3969/j.issn.1006-4303.2005.02.004
cited:
year:
2005
Last Update：2024-01-02 23:10:35
CEFADROXILMONOHYDRATE - Clinical evaluation of cefadroxil
Author:
Abstract:
Cefadroxil is the first generation of semi-synthetic cephalosporins, with strong antibacterial, enzyme resistance, high efficacy, long duration of drug concentration and low toxicity, at present, it is widely used in clinical practice. The pharmacokinetic characteristics, antibacterial activity and clinical application were comprehensively evaluated. 1 pharmacokinetic characteristics of cefadroxil and Cefalexin structural differences in the aromatic ring...
DOI:
CNKI:SUN:ZGYZ.0.1999-04-020
cited:
year:
1999
Last Update：2023-08-16 22:09:50
CEFADROXILMONOHYDRATE - Cefoxitin-benzyl tablets for pets and preparation method thereof [invention patent]
from Baidu Library
Application (patent) number:
CN202010198385.2
application date:
2020-03-19
Public/Announcement Number:
CN111388432A
Public/announcement date:
2020.07.10
applicant (patent):
Weifang Fubang Pharmaceutical Co., Ltd.
inventor:
National and provincial code:
CN370784
Abstract:
The present invention discloses a cefadroxil tablet for pet use and a preparation method thereof. Each tablet contains cefadroxil including but not limited to 0.125g,0.25g and 0.5g. The cefadroxil tablet for pets comprises the following components in parts by weight: cefadroxil 25-42%, bulking agent 30-60%, disintegrating agent 3-12%, flavoring agent 0.1-1%, lubricant 1-5%. The cefoxitin tablets for pets of the present invention are directly compressed by dry method, which avoids the production conditions of high temperature and high humidity compared with the existing products on the market, under the conditions of high humidity and the like, the content and related substances have no obvious change, and the stability is better; And the in vitro dissolution test shows that the dissolution rate of the cefoxitin benzyl tablets for pets provided by the present invention is obviously better than that of the commercially available products, it shows that the bioavailability of this product is better. The invention of cefoxitin benzyl tablets, stability, good curative effect
Last Update：2023-08-16 22:09:50
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Product Name: Cefadroxil Request for quotation
CAS: 66592-87-8
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info@tnjchem.com
Mobile: 0086 189 4982 3763
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Product List: View Catalog
CAS: 66592-87-8
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
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View History
CEFADROXILMONOHYDRATE
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4-[4-(氯甲基)-1,3-噻唑-2-基]苯甲酸甲酯
舒更葡糖钠杂质04
熊去氧胆酸杂质16
1-(3-硝基苄基)-1H-吲哚-2,3-二酮
1-(4-氟苯基)环己烷甲胺
舒更葡糖杂质14
(2-丙氧基苄基)肼盐酸盐
3-溴-1-(1-乙氧基乙基)-1,2,4-1H-三氮唑
4-(5-巯基四唑-1-基)苯甲酸
4-[4-(氯甲基)-1,3-噻唑-2-基]苯甲酸甲酯
舒更葡糖钠杂质04
熊去氧胆酸杂质16
1-(3-硝基苄基)-1H-吲哚-2,3-二酮