辛二酸二琥珀酰亚胺
Disuccinimidyl subera
CAS: 68528-80-3
Molecular Formula: C16H20N2O8
辛二酸二琥珀酰亚胺 - Names and Identifiers
| Name | Disuccinimidyl subera |
| Synonyms | DSS DSS Crosslinker Disuccinimidyl subera DISUCCINIMIDYL SUBERATE Di(N-succinimidyl) Suberate DISUCCINIMIDYL OCTANEDIOATE Bis-(N-succinimidyl)-suberate n-hydroxysuccinimidesubericacidester SUBERIC ACID BIS(N-HYDROXY-SUCCINIMIDE ESTER) |
| CAS | 68528-80-3 |
| EINECS | 614-576-1 |
| InChIKey | ZWIBGKZDAWNIFC-UHFFFAOYSA-N |
辛二酸二琥珀酰亚胺 - Physico-chemical Properties
| Molecular Formula | C16H20N2O8 |
| Molar Mass | 368.34 |
| Density | 1.295 g/cm3 |
| Melting Point | 169-170°C |
| Boling Point | 513.5±60.0 °C(Predicted) |
| Water Solubility | Insoluble in water. Soluble in chloroform: 50 mg/mL. |
| Solubility | chloroform: 50mg/mL |
| Appearance | powder |
| Color | White to Almost white |
| Storage Condition | 2-8°C |
| In vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
辛二酸二琥珀酰亚胺 - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29171900 |
辛二酸二琥珀酰亚胺 - Reference Information
| biological activity | DSS Crosslinker (disccinidiyl suberate) is a kind of cross-linking agent with the same and dual function, it is also a non-cleavable ADC linker and can be used for the synthesis of antibody-drug conjugate drugs (ADCs). |
| Use | a homologous bifunctional crosslinker with amine reactivity. The linkage to the primary amine-containing molecule is typically via an amide bond buffered to pH 6.5 (8.5-). A linker containing 8 atoms. |
Last Update：2024-04-10 22:29:15
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