丙炔基-二聚乙二醇-氨基
2-[2-(2-Propynyloxy)ethoxy]ethylamine
CAS: 944561-44-8
Molecular Formula: C7H13NO2
丙炔基-二聚乙二醇-氨基 - Names and Identifiers
丙炔基-二聚乙二醇-氨基 - Physico-chemical Properties
| Molecular Formula | C7H13NO2 |
| Molar Mass | 143.18 |
| Density | 0.992±0.06 g/cm3(Predicted) |
| Boling Point | 213.8±20.0 °C(Predicted) |
| pKa | 8.72±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.4590 to 1.4630 |
| Physical and Chemical Properties | Bioactive Propargyl-PEG2-amine is a non-cleavable ADC linker used in the synthesis of antibody-coupled drugs (ADCs). Propargyl-PEG2-amine is a PROTAC linker and belongs to the PEG class. Propargyl-PEG2-NH2 can be used to synthesize a series of PROTAC molecules. |
| In vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
丙炔基-二聚乙二醇-氨基 - Risk and Safety
| UN IDs | UN 2735 8/PG II |
| Hazard Class | 8 |
| Packing Group | II |
丙炔基-二聚乙二醇-氨基 - Reference Information
| biological activity | Propargyl-PEG2-amine is a non-cleavable ADC linker for the synthesis of antibody-coupled drugs (ADCs). Propargyl-PEG2-amine is a PROTAC linker and belongs to the PEG class. Propargyl-PEG2-NH2 can be used to synthesize a series of PROTAC molecules. |
| target | Non-cleavable PEGs |
| in vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
Last Update：2024-04-09 21:04:16
Supplier List
Spot supply
Product Name: Propargyl-PEG2-amine Visit Supplier Webpage Request for quotationCAS: 944561-44-8
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: 2-[2-(2-Propynyloxy)ethoxy]ethylamine Visit Supplier Webpage Request for quotationCAS: 944561-44-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 2-[2-(2-Propynyloxy)ethoxy]ethylamine Visit Supplier Webpage Request for quotationCAS: 944561-44-8
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: 2-[2-(2-Propynyloxy)ethoxy]ethylamine Visit Supplier Webpage Request for quotation
CAS: 944561-44-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 944561-44-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: Propargyl-PEG2-amine Visit Supplier Webpage Request for quotationCAS: 944561-44-8
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: 2-[2-(2-Propynyloxy)ethoxy]ethylamine Visit Supplier Webpage Request for quotationCAS: 944561-44-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 2-[2-(2-Propynyloxy)ethoxy]ethylamine Visit Supplier Webpage Request for quotationCAS: 944561-44-8
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: 2-[2-(2-Propynyloxy)ethoxy]ethylamine Visit Supplier Webpage Request for quotation
CAS: 944561-44-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 944561-44-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
丙炔基-二聚乙二醇-氨基
4-羟基-2-巯基嘧啶-5-甲酸
硅酸锌(1:2)
(2-氨基甲基-哌啶-1-基)-(2-氯-吡啶-3-基)-甲酮盐酸盐
[4-(Aminomethyl)phenyl]phenyl-methanone HCl
5 - 氨基-3 - 甲基吡嗪-2 - 甲腈
(4-溴-1-甲基-3-吡唑基)甲醇
2-氨基-4-(4-环己基苯基)-5-甲基-噻吩-3-羧酸甲酯
2-[Dimethoxyphosphinyl]-4-(1,3-dioxolan-2-yl)butyric acid methyl ester
TITANIUM TRIS(DODECYLBENZENESULFONATE)ISOPROPOXIDE
4-羟基-2-巯基嘧啶-5-甲酸
硅酸锌(1:2)
(2-氨基甲基-哌啶-1-基)-(2-氯-吡啶-3-基)-甲酮盐酸盐
[4-(Aminomethyl)phenyl]phenyl-methanone HCl
5 - 氨基-3 - 甲基吡嗪-2 - 甲腈
(4-溴-1-甲基-3-吡唑基)甲醇
2-氨基-4-(4-环己基苯基)-5-甲基-噻吩-3-羧酸甲酯
2-[Dimethoxyphosphinyl]-4-(1,3-dioxolan-2-yl)butyric acid methyl ester
TITANIUM TRIS(DODECYLBENZENESULFONATE)ISOPROPOXIDE