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berberinsulfate

berberine sulphate

CAS: 316-41-6

Molecular Formula: C20H18NO8S-

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berberinsulfate - Names and Identifiers

Name berberine sulphate
Synonyms berberinsu
berberinsulfate
berberine sulphate
neutralberberinesulfate
3-benzodioxolo(5,6-a)quinolizinium,5,6-dihydro-9,10-dimethoxy-benzo(g)-s
7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-berbiniusulfat
3-benzodioxolo(5,6-a)quinolizinium,5,6-dihydr0-9,10-dimethoxy-benzo(g)-sul
5,6-Dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium sulfate
Bis(9,10-dimethoxy-5,6-dihydro[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ium) sulfate
Bis(9,10-dimethoxy-5,6-dihydro[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium) sulfate
CAS 316-41-6
EINECS 206-258-2
InChI InChI=1/C20H18NO4.H2O4S.3H2O/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;1-5(2,3)4;;;/h3-4,7-10H,5-6,11H2,1-2H3;(H2,1,2,3,4);3*1H2/q+1;;;;/p-1
InChIKey OJVABJMSSDUECT-UHFFFAOYSA-L

berberinsulfate - Physico-chemical Properties

Molecular FormulaC20H18NO8S-
Molar Mass432.42
Water Solubilityalmost transparency
Appearancepowder to crystal
ColorOff white to yellow powder
Merck14,1154
Storage ConditionInert atmosphere,Room Temperature
UseAntibacterial, used to treat intestinal infections caused by Shigella

berberinsulfate - Risk and Safety

UN IDs1544
RTECSDR9867300
HS Code29399990
Hazard Class6.1(b)
Packing GroupIII
ToxicityLD50 ipr-mus: 26,400 mg/kg NIIRDN 6,770,82

berberinsulfate - Reference

Reference
Show more
1. Mannan. Effect of berberine on expression of cell adhesion molecules in ischemic brain regions of rats with focal cerebral ischemia-reperfusion [J]. Chinese Journal of Experimental prescriptions, 2011, 17(14).
2. Xu, Jun. "Improved approaches and strategies for analyzing calculations of medical herbs." (2016).

berberinsulfate - Nature

Open Data Verified Data

This product is an alkaloid extracted from three needles and other plants. The crystals obtained from diethyl ether are yellow needle-like crystals, melting point 145 ° C., soluble in water (1:4.5), but slowly dissolving. Its hydrochloride is bright yellow crystals or powder, odorless, bitter taste, soluble in water (1:400), soluble in boiling water, insoluble in ethanol, ether and chloroform.

Last Update:2024-01-02 23:10:35

berberinsulfate - Preparation Method

Open Data Verified Data

0.2% G of three pieces of needle flakes or coarse powder were taken and immersed for 36 hours in a 5-fold volume aqueous solution of by volume sulfuric acid for 36 hours each time, and stirring was continued during the extraction. Filter the leaching solution, add lime powder to adjust the pH value to 9~11, filter out the precipitate, add industrial salt with mass concentration (W/V) of 7% solid to the filtrate, and stir to dissolve it, filtration after placement. The filtered precipitate was washed with a small amount of water for 1-2 times to remove excess salt, suspended and dried at 80 ° C. To obtain crude berberine. Take the crude product with appropriate amount of water to dissolve (the amount of water is about 30 times the dry product or 10 times the wet product), heat for 30 min, filter while hot, take the filtrate, and then add concentrated hc1, the pH value is adjusted to 1-2, placed for 2H, filtered, and the filtered precipitate is washed with a small amount of distilled water until the pH value is 5, and then dried at 80 ° C. To obtain berberine hydrochloride excellent product.

Last Update:2022-01-01 11:15:01

berberinsulfate - Use

Open Data Verified Data

Berberine has good antibacterial effect, and is effective for dysentery, pertussis, scarlet fever, small/L Pneumonia, various Acute suppurative infections, acute external eye inflammation and suppurative otitis media.

Last Update:2022-01-01 11:15:02
berberinsulfate
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Shanghai Macklin Biochemical Co., Ltd
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CAS: 316-41-6
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Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: Berberine Sulfate Hydrate Visit Supplier Webpage Request for quotation
CAS: 316-41-6
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
MedChemExpress (MCE)
Multiple SpecificationsSpot supply
Product Name: Berberine hemisulfate Visit Supplier Webpage Request for quotation
CAS: 316-41-6
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: berberine sulphate Visit Supplier Webpage Request for quotation
CAS: 316-41-6
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Shanghai Yuanye Bio-Technology Co., Ltd.
Spot supply
Product Name: BERBERINE SULFATE TRIHYDRATE Visit Supplier Webpage Request for quotation
CAS: 316-41-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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