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Sarafloxacinbase

Sarafloxacin

CAS: 98105-99-8

Molecular Formula: C20H17F2N3O3

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Sarafloxacinbase - Names and Identifiers

Name Sarafloxacin
Synonyms A-56620
98105-99-8
SARAFLOZACIN
Sarafloxacin
Sarafloxacinbase
6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-piperazino-3-quinolinecarboxylic acid
6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid
6-fluoro-1-(4-fluorophenyl)-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
3-quinolinecarboxylic acid, 6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-
1,4-Dihydro-6-fluoro-7-(piperazine-1-yl)-1-(4-fluorophenyl)-4-oxoquinoline-3-carboxylic acid
CAS 98105-99-8
EINECS 1806241-263-5
InChI InChI=1/C20H17F2N3O3/c21-12-1-3-13(4-2-12)25-11-15(20(27)28)19(26)14-9-16(22)18(10-17(14)25)24-7-5-23-6-8-24/h1-4,9-11,23H,5-8H2,(H,27,28)

Sarafloxacinbase - Physico-chemical Properties

Molecular FormulaC20H17F2N3O3
Molar Mass385.36
Density1.436±0.06 g/cm3(Predicted)
Melting Point282-285 °C(Solv: chloroform (67-66-3); ethanol (64-17-5))
Boling Point621.4±55.0 °C(Predicted)
Flash Point329.6°C
Solubility Slightly soluble in sodium hydroxide solution, slightly soluble in methanol.
Vapor Presure2.67E-16mmHg at 25°C
AppearanceWhite or yellowish crystalline powder
ColorOff-White to Pale Beige
pKa6.17±0.41(Predicted)
Storage Condition2-8°C(protect from light)
StabilityHygroscopic
Refractive Index1.633
MDLMFCD00865974
Physical and Chemical PropertiesSarfloxacin hydrochloride (Sarafloxacin Monohydrochloride):C20 H17F2N3O3?HCl. [91296-87-6]. The melting point of monohydrate is> 275 ℃.
UseBroad-spectrum antibacterials

Sarafloxacinbase - Risk and Safety

Safety Description24/25 - Avoid contact with skin and eyes.
HS Code29339900

Sarafloxacinbase - Reference

Reference
Show more
1. [IF=6.057] Song Hu et al."Reliable performance of aggregation-induced emission nanoparticle-based lateral flow assay for norfloxacin detection in nine types of animal-derived food."Talanta. 2020 Nov;219:121245
2. [IF=2.863] Yu Zhang et al."Antibiotic residues in cattle and sheep meat and human exposure assessment in southern Xinjiang, China."Food Sci Nutr. 2021 Nov;9(11):6152-6161
3. [IF=2.896] Chunhui Lu et al."Rapid quantitative detection of chloramphenicol in three food products by lanthanide-labeled fluorescent-nanoparticle immunochromatographic strips."Analytical Methods. 2022 May;14(17):1705-1714

Sarafloxacinbase - Nature

Open Data Verified Data

white or light yellow crystalline powder, odorless, slightly bitter in taste, darkened in light. Melting point> 275 °c. Slightly soluble in sodium hydroxide solution, slightly soluble in methanol.

Last Update:2024-01-02 23:10:35

Sarafloxacinbase - Preparation Method

Open Data Verified Data

condensation of 2,4-= chloro-5-fluoroacetophenone with diethyl carbonate followed by condensation with triethyl orthoformate followed by condensation with p-fluoroaniline. Under the action of sodium hydride, the product is refluxed in ethylene glycol dimethyl ether. The hydrolyzed product was condensed with piperazine to obtain sarafloxacin.

Last Update:2022-01-01 09:08:57

Sarafloxacinbase - Use

Open Data Verified Data

quinolones. Can be used for the prevention and treatment of livestock and poultry colibacillosis, Staphylococcus disease, anaerobic bacteria also have a strong killing effect, can also be used for aquaculture disease prevention and control, such as shrimp Vibrio disease, bighead intestinal sepsis and so on.

Last Update:2022-01-01 09:08:57
Sarafloxacinbase
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MedChemExpress (MCE)
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CAS: 98105-99-8
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MedChemExpress (MCE)
Multiple SpecificationsSpot supply
Product Name: A-56620 Visit Supplier Webpage Request for quotation
CAS: 98105-99-8
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
SKYRUN INDUSTRIAL CO.,LTD
Spot supply
Product Name: Sarafloxacin Visit Supplier Webpage Request for quotation
CAS: 98105-99-8
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
Wechat: chinaskyrun
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Sarafloxacin Visit Supplier Webpage Request for quotation
CAS: 98105-99-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: Sarafloxacin Visit Supplier Webpage Request for quotation
CAS: 98105-99-8
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Yuanye Bio-Technology Co., Ltd.
Multiple SpecificationsSpot supply
Product Name: Sarafloxacin Visit Supplier Webpage Request for quotation
CAS: 98105-99-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
Sarafloxacinbase
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