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RG3039(PF-06687859)

RG3039

CAS: 1005504-62-0

Molecular Formula: C21H23Cl2N5O

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RG3039(PF-06687859) - Names and Identifiers

Name RG3039
Synonyms RG3039
RG3039
RG-3039
EOS-61154
EOS-62326
PF-6687859
RG3039(PF-06687859)
5-[[1-(2,6-Dichlorobenzyl)piperidin-4-yl]methoxy]quinazoline-2,4-diamine
5-((1-(2,6-dichlorobenzyl)piperidin-4-yl)methoxy)quinazoline-2,4-diaminedihydrochloride
CAS 1005504-62-0

RG3039(PF-06687859) - Physico-chemical Properties

Molecular FormulaC21H23Cl2N5O
Molar Mass432.35
Density1.375±0.06 g/cm3(Predicted)
Boling Point648.1±65.0 °C(Predicted)
pKa7.82±0.30(Predicted)
Storage Condition2-8℃

RG3039(PF-06687859) - Reference Information

biological activity RG3039 (PF-06687859, PF 6687859, Quinazoline 495) is a brain permeation inhibitor of oral bioavailable mRNA-lowering enzyme DcpS, with IC50 and IC90 values of 4.2 nM and 40 nM respectively.
target TargetValue dcpS (cell-free say) 4.2 nm dcps (cell-free say) 40 nm (ic90)
TargetValue
DcpS (Cell-free assay) 4.2 nM
40 nM(IC90)
Last Update:2024-04-10 22:29:15
RG3039(PF-06687859)
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MedChemExpress (MCE)
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Product Name: PF-06687859 Visit Supplier Webpage Request for quotation
CAS: 1005504-62-0
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Rg3039(pf-06687859) Visit Supplier Webpage Request for quotation
CAS: 1005504-62-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: RG3039 Visit Supplier Webpage Request for quotation
CAS: 1005504-62-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: RG3039 Visit Supplier Webpage Request for quotation
CAS: 1005504-62-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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RG3039(PF-06687859)
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