N-甲基-4-氨基-2-氟-苯甲酰胺
N-Methyl-4-amino-2-fluoro-benzamide
CAS: 915087-25-1
Molecular Formula: C8H9FN2O
N-甲基-4-氨基-2-氟-苯甲酰胺 - Names and Identifiers
| Name | N-Methyl-4-amino-2-fluoro-benzamide |
| Synonyms | Enzalutamide ITS-3 Enzalutamide Impurity 20 n-methyl-2-fluoro-4-aminobenzamide 4-amino-2-fluoro-n-methylbenzamide 4-AMINO-2-FLUORO-N-METHYLBENZAMIDE N-Methyl-2-fluoro-4-aminobenzamide 4-amino-2-fluoro-N-menthylbenzamide N-Methyl-4-amino-2-fluoro-benzamide 2. 4-aMino-2-fluoro-N-MethylbenzaMide BenzaMide, 4-aMino-2-fluoro-N-Methyl- |
| CAS | 915087-25-1 |
| InChI | InChI=1S/C8H9FN2O/c1-11-8(12)6-3-2-5(10)4-7(6)9/h2-4H,10H2,1H3,(H,11,12) |
N-甲基-4-氨基-2-氟-苯甲酰胺 - Physico-chemical Properties
| Molecular Formula | C8H9FN2O |
| Molar Mass | 168.17 |
| Density | 1.234 |
| Melting Point | 160 - 163°C |
| Boling Point | 320℃ |
| Flash Point | 147℃ |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | 14.12±0.46(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Stability | Moisture Sensitive |
| Use | This product is for scientific research only and shall not be used for other purposes. |
N-甲基-4-氨基-2-氟-苯甲酰胺 - Introduction
N-Methyl-4-amino-2-fluoro-benzamide is an organic compound having the chemical formula CH3CONHPhNH2, wherein Ph represents a phenyl group. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: The N-Methyl-4-amino-2-fluoro-benzamide is a white or off-white crystalline solid.
-Solubility: It has a certain solubility in some organic solvents, such as methanol, ethanol and dimethyl sulfoxide.
-Melting point: approximately 160-165°C.
Use:
- N-Methyl-4-amino-2-fluoro-benzamide can be used as intermediates in organic synthesis.
-In the field of medicine, it may be used to synthesize biologically active compounds.
-Due to its specific structure, it may have other potential applications, but further research is needed.
Method:
- N-Methyl-4-amino-2-fluoro-benzamide can be synthesized by adding methylamine and fluorine atoms to benzoyl chloride solution.
-The specific reaction conditions and synthesis steps need to be optimized according to the specific situation.
Safety Information:
-The toxicity and danger of N-Methyl-4-amino-2-fluoro-benzamide has not been fully assessed. Appropriate laboratory safety practices and personal protective measures should be followed during use and handling.
-Avoid direct contact with skin and eyes, avoid inhalation and ingestion.
-In case of accidental contact, immediately flush the affected area with plenty of water and seek medical help.
Nature:
-Appearance: The N-Methyl-4-amino-2-fluoro-benzamide is a white or off-white crystalline solid.
-Solubility: It has a certain solubility in some organic solvents, such as methanol, ethanol and dimethyl sulfoxide.
-Melting point: approximately 160-165°C.
Use:
- N-Methyl-4-amino-2-fluoro-benzamide can be used as intermediates in organic synthesis.
-In the field of medicine, it may be used to synthesize biologically active compounds.
-Due to its specific structure, it may have other potential applications, but further research is needed.
Method:
- N-Methyl-4-amino-2-fluoro-benzamide can be synthesized by adding methylamine and fluorine atoms to benzoyl chloride solution.
-The specific reaction conditions and synthesis steps need to be optimized according to the specific situation.
Safety Information:
-The toxicity and danger of N-Methyl-4-amino-2-fluoro-benzamide has not been fully assessed. Appropriate laboratory safety practices and personal protective measures should be followed during use and handling.
-Avoid direct contact with skin and eyes, avoid inhalation and ingestion.
-In case of accidental contact, immediately flush the affected area with plenty of water and seek medical help.
Last Update：2024-04-09 21:04:16
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View History
N-甲基-4-氨基-2-氟-苯甲酰胺
3-溴-2,6-二氟吡啶2,6-二氟-3-溴吡啶
1-[3,5-bis(phenylmethoxy)phenyl]-2,2-dihydroxyethanone
(R)-2-(4-HYDROPHENOXY)PROPIONIC ACID
ALPHA-HYDROXY-DL-METHIONINE CALCIUM SALT
PROPYL TRIMETHICONE
LITHIUM TRI-T-BUTOXYALUMINOHYDRIDE
Hexadecanoic acid, 2-ethylhexyl ester
L-1-FMOC-乳酸
2-DIMETHYLAMINO-PYRIMIDINE-5-BORONIC ACID HYDROCHLORIDE
3-溴-2,6-二氟吡啶2,6-二氟-3-溴吡啶
1-[3,5-bis(phenylmethoxy)phenyl]-2,2-dihydroxyethanone
(R)-2-(4-HYDROPHENOXY)PROPIONIC ACID
ALPHA-HYDROXY-DL-METHIONINE CALCIUM SALT
PROPYL TRIMETHICONE
LITHIUM TRI-T-BUTOXYALUMINOHYDRIDE
Hexadecanoic acid, 2-ethylhexyl ester
L-1-FMOC-乳酸
2-DIMETHYLAMINO-PYRIMIDINE-5-BORONIC ACID HYDROCHLORIDE