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MLN2238

(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid

CAS: 1072833-77-2

Molecular Formula: C14H19BCl2N2O4

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MLN2238 - Names and Identifiers

Name (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid
Synonyms CS-1976
MLN2238
IXAZOMIB
IxazoMib
MLN 2238
MLN-2238
ixazomib(MLN2238)
1-(2-(2,5-dichlorobenzamido)acetamido)- 3-methylbutylboronic acid
(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid
B-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid
CAS 1072833-77-2
EINECS 810-246-8

MLN2238 - Physico-chemical Properties

Molecular FormulaC14H19BCl2N2O4
Molar Mass361.03
Density1.306
Melting Point>142°C (subl.)
Water SolubilityDMSO (Sparingly), Methanol (Slightly)
AppearanceShape Solid Color White to Pale Yellow
pKa9.67±0.43(Predicted)
Storage Condition-20°C Freezer
UseOn November 20, 2015, the US FDA approved the launch of the new drug Isazomi (Ixazomib) capsule developed by Millennium (Millennium) Pharmaceutical Company under Takeda, Japan, under the trade name Ninlaro. Isazomil is an oral proteasome inhibitor that works by inhibiting the enzyme activity of multiple myeloma cells to prevent the growth and survival of cancer cells. Isazomil is combined with lenalidomide and dexamethasone Treatment of treated patients with multiple myeloma. Multiple myeloma is a rare cancer. There are about 20,000 new cases in the United States every year and about 114,000 in the world.

MLN2238 - Preparation solution concentration reference

 1mg5mg10mg
1 mM2.77 ml13.849 ml27.699 ml
5 mM0.554 ml2.77 ml5.54 ml
10 mM0.277 ml1.385 ml2.77 ml
5 mM0.055 ml0.277 ml0.554 ml
Last Update:2024-01-02 23:10:35
MLN2238
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MedChemExpress (MCE)
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CAS: 1072833-77-2
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CAS: 1072833-77-2
Tel: 18301782025
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Mobile: 18021002903
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MedChemExpress (MCE)
Multiple SpecificationsSpot supply
Product Name: MLN2238 Visit Supplier Webpage Request for quotation
CAS: 1072833-77-2
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
SKYRUN INDUSTRIAL CO.,LTD
Spot supply
Product Name: MLN2238 Visit Supplier Webpage Request for quotation
CAS: 1072833-77-2
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
Wechat: chinaskyrun
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Ixazomib Visit Supplier Webpage Request for quotation
CAS: 1072833-77-2
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: MLN2238 Visit Supplier Webpage Request for quotation
CAS: 1072833-77-2
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Yuanye Bio-Technology Co., Ltd.
Spot supply
Product Name: MLN2238 Visit Supplier Webpage Request for quotation
CAS: 1072833-77-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
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