Molecular Formula | C22H28ClNO |
Molar Mass | 357.92 |
Density | 1.088±0.06 g/cm3(Predicted) |
Boling Point | 447.2±35.0 °C(Predicted) |
pKa | 8.87±0.20(Predicted) |
Physical and Chemical Properties | STastatin hydrochloride (Setastine Hydrochloride):C22H28C1NO?HCI. [59767-13-4]. Crystallization, melting point 170~171 ℃. |
use | H1 receptor antagonist. Used for allergic rhinitis, urticaria, allergic dermatitis. |
production method | method 1: compound (I) is dissolved in benzene, and then N-(2-chloroethyl) actaenin is added to react with sodium amide to obtain statin. Method 2: The compound (II) was reacted with N-(2-hydroxyethyl) actahepene to obtain stastine. Method 3: React with compound (Ⅲ) and azepenin, and stine. |