64294-95-7

Name	Setastine
Synonyms	Loderix Setastin Setastine EGIS-2062 EGYT-2062 1-(2-(1-(4-Chlorophenyl)-1-phenylethoxy)ethyl)azepane 1H-AZEPINE, 1-[2-[1-(4-CHLOROPHENYL)-1-PHENYLETHOXY]ETHYL]HEXAHYDRO- 1-[2-[(4-Chloro-α-methyl-α-phenylbenzyl)oxy]ethyl]-hexahydro-1H-azepine
CAS	64294-95-7

Molecular Formula	C22H28ClNO
Molar Mass	357.92
Density	1.088±0.06 g/cm3(Predicted)
Boling Point	447.2±35.0 °C(Predicted)
pKa	8.87±0.20(Predicted)
Physical and Chemical Properties	STastatin hydrochloride (Setastine Hydrochloride):C22H28C1NO?HCI. [59767-13-4]. Crystallization, melting point 170~171 ℃.

use	H1 receptor antagonist. Used for allergic rhinitis, urticaria, allergic dermatitis.
production method	method 1: compound (I) is dissolved in benzene, and then N-(2-chloroethyl) actaenin is added to react with sodium amide to obtain statin. Method 2: The compound (II) was reacted with N-(2-hydroxyethyl) actahepene to obtain stastine. Method 3: React with compound (Ⅲ) and azepenin, and stine.

Last Update：2024-04-09 20:52:54

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