ECONAZOLENITRATE,BP
Econazole nitrate
CAS: 24169-02-6;68797-31-9
Molecular Formula: C18H16Cl3N3O4
ECONAZOLENITRATE,BP - Names and Identifiers
ECONAZOLENITRATE,BP - Physico-chemical Properties
| Molecular Formula | C18H16Cl3N3O4 |
| Molar Mass | 444.7 |
| Melting Point | 162°C |
| Water Solubility | <0.1 g/100 mL at 19 ºC |
| Solubility | DMSO 89 mg/mL Water <1 mg/mL Ethanol 5 mg/mL |
| Appearance | White crystal |
| Color | white to off-white |
| Merck | 14,3502 |
| Storage Condition | Inert atmosphere,Room Temperature |
| MDL | MFCD00058160 |
| Physical and Chemical Properties | Melting point 162°C water-soluble <0.1g/100 mL at 19°C |
ECONAZOLENITRATE,BP - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36/38 - Irritating to eyes and skin. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S36/37 - Wear suitable protective clothing and gloves. |
| WGK Germany | 3 |
| RTECS | NI4450000 |
| HS Code | 29332900 |
| Toxicity | LD50 in mice, rats (mg/kg): 462.7, 667.7 orally (Thienpont) |
ECONAZOLENITRATE,BP - Standard
Authoritative Data Verified Data
This product is 9,10-didehydro-bis [(S)-2-hydroxy-1-methylethyl]-6-methylergoline-8B-carboxamide maleate. Calculated as dried product, including C19H23N302 • C4H404 shall not be less than 98.0%.
Last Update：2024-01-02 23:10:35
ECONAZOLENITRATE,BP - Trait
Authoritative Data Verified Data
- This product is white or white-like crystalline powder; Odorless; Slightly hygroscopic; Easy to deteriorate in light.
- This product is slightly soluble in water, slightly soluble in ethanol, and insoluble in chloroform or ether.
specific rotation
take this product, precision weighing, adding water to dissolve and quantitatively dilute to make a solution containing about 10mg per lml, and determine according to law (General rule 0621), and the specific rotation is 53. To 56..
Last Update：2022-01-01 11:31:37
ECONAZOLENITRATE,BP - Differential diagnosis
Authoritative Data Verified Data
- the aqueous solution of this product shows blue fluorescence.
- take about 1 mg of this product, add 1 ml of water to dissolve, add 2ml of p-dimethylaminobenzaldehyde test solution, after 5 minutes, it shows dark blue.
- The infrared absorption spectrum of this product should be consistent with that of the control (Spectrum set 32).
Last Update：2022-01-01 11:31:38
ECONAZOLENITRATE,BP - Exam
Authoritative Data Verified Data
acidity
take 0.10g of this product, Add 10ml of water to dissolve, and measure according to law (General rule 0631). The pH value should be 3.6~4.4.
clarity of the solution
take 0.10g of this product and add 10ml of water to dissolve. The solution should be clarified.
Related substances
take this product, precision weighing, add ethanol-concentrated ammonia solution (9:1) dissolve and quantitatively dilute to prepare a solution containing 5mg per lml and a solution containing 0.2mg per lml, respectively, as the test solution (1) and the test solution (2 ) ; another ergometrine maleate reference substance was precisely weighed, dissolved and quantitatively diluted with the above solvent to prepare a solution containing 5mg per 1 ml as a reference solution. According to the thin layer chromatography (General 0502) test, absorb the above three kinds of solution each 1UL, respectively, on the same silica gel G thin layer plate, with chloroform-methanol-water (25:8:1) for the development of the agent, expand, dry, set the UV light (365nm) under the view. The position and color of the main spot of the test solution (1) should be the same as the main spot of the reference solution, such as the impurity spot, and the color is compared with the corresponding impurity spot of the reference solution, shall not be deeper, and shall not show impurity spots other than the reference solution; Test solution (2) shall not show any impurity spots except the main spot.
loss on drying
take this product, put the phosphorus pentoxide dryer to dry to constant weight, weight loss shall not exceed 2.0% (General rule 0831).
Last Update：2022-01-01 11:31:38
ECONAZOLENITRATE,BP - Content determination
Authoritative Data Verified Data
take about 60mg of this product, precision weighing, add glacial acetic acid 20ml to dissolve, add 1 drop of crystal violet indicator solution, and titrate with perchloric acid titration solution (0.05mol/L) until the solution shows blue and green, the results of the titration were corrected by a blank test. Each 1 ml perchloric acid titration solution (0.05mol/L) corresponds to 22.07 mg of c19h23n302. C4H404.
Last Update：2022-01-01 11:31:39
ECONAZOLENITRATE,BP - Category
Authoritative Data Verified Data
uterine contraction drug.
Last Update：2022-01-01 11:31:39
ECONAZOLENITRATE,BP - Storage
Authoritative Data Verified Data
shading, sealing, storage in cold place.
Last Update：2022-01-01 11:31:39
ECONAZOLENITRATE,BP - Ergometrine Maleate Injection
Authoritative Data Verified Data
This product is a sterilized aqueous solution of ergometrine maleate. Ergometrine Maleate (19H23N302 • C4H404) shall be between 90.0% and 110.0% of the labeled amount.
trait
This product is colorless or almost colorless clear liquid, with slight blue fluorescence.
identification
take an appropriate amount of this product (about 0.5mg equivalent to ergometrine maleate), add 2ml of p-dimethylaminobenzaldehyde test solution, and after 5 minutes, it shows a dark blue color.
examination
The pH value should be 3. 0 to 5. 0 (General 0631).
Others should comply with the relevant provisions under injections (General rule 0102).
Content determination
take an appropriate amount of this product accurately (about 1.5mg equivalent to ergometrine maleate), put it in a 25ml measuring flask, dilute it with water to scale, shake it well, take lml accurately, put it in a test tube with a plug and scale, add 1% tartaric acid solution (1 ml) and p-dimethylaminobenzaldehyde solution (4ml) precisely, shake well, stand for 5 minutes, measure absorbance at the wavelength of 550nm according to ultraviolet-visible spectrophotometry (General rule 0401); another 15mg ergometrine maleate reference was added into 250ml measuring flask, dissolved with appropriate amount of water and diluted to the scale. It is obtained by calculation.
category
The same as ergometrine maleate.
specification
- lml:0.2mg
- lml:0.5mg
storage
light shielding, closed, stored in cold place.
Last Update：2022-01-01 11:31:40
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Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Multiple SpecificationsSpot supply
Product Name: Econazole nitrate Visit Supplier Webpage Request for quotationCAS: 24169-02-6
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Econazole nitrate Visit Supplier Webpage Request for quotationCAS: 24169-02-6
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Product Name: Econazole nitrate Request for quotation
CAS: 24169-02-6
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 24169-02-6
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Spot supply
Product Name: Econazole Nitrate Visit Supplier Webpage Request for quotationCAS: 24169-02-6
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Multiple SpecificationsSpot supply
Product Name: Econazole nitrate Visit Supplier Webpage Request for quotationCAS: 24169-02-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
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View History
ECONAZOLENITRATE,BP
TetraheptylammoniumBromideGrForHplc
N-ACYL-D-GLUCOSAMINE: OXYGEN 1-OXIDOREDUCTASE
(3R)-(+)-3-(ETHYLAMINO)PYRROLIDINE
1,1-联苯基肼盐酸盐
4H-1-Benzopyran-4-one, 5,6,7,8-tetrahydro-6,7,8-trihydroxy-2-(2-phenylethyl)-, (6S,7S,8S)-
TetraheptylammoniumBromideGrForHplc
N-ACYL-D-GLUCOSAMINE: OXYGEN 1-OXIDOREDUCTASE
(3R)-(+)-3-(ETHYLAMINO)PYRROLIDINE
1,1-联苯基肼盐酸盐
4H-1-Benzopyran-4-one, 5,6,7,8-tetrahydro-6,7,8-trihydroxy-2-(2-phenylethyl)-, (6S,7S,8S)-