Molar Mass | 1526.03 |
Storage Condition | Room Temprature |
Refractive Index | -68 |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
pan , Tao Liping , Li Aizhen , Chen Xinzhi
Abstract:
A RP-HPLC method was established for the simultaneous determination of total chondroitin sulfate and its components A,B,C,D. A C18 column was used with the mobile phase of acetonitrile-0.5% phosphoric acid-Isopropanol (15:85:1) at the detection wavelength of 209nm and the column temperature of 40 ℃. The linear range of chondroitin sulfate was 0.4~2 mg/mL (r = 0.9997). The average recovery was 99.3% with RSD of 1.16%.
Key words:
chondroitin sulfate high performance liquid chromatography assay
DOI:
10.3969/j.issn.1001-8255.2007.09.019
cited:
year:
2007
202120212321
applicant (patent):
Binzhou College
inventor:
CN201510008740.4
application date:
2015-01-08
Public/Announcement Number:
CN104491859A
Public/announcement date:
2015.04.08
applicant (patent):
Institute of Medical Biology, Chinese Academy of Medical Sciences
inventor:
Wang Chen Yun , Wang , Sun Jing , Li Yanhan , Ummini , Li Jianfang , ha , Yun Hu , Shi Jiandong
National and provincial code:
CN530102
Abstract:
The present invention provides an application of chondroitin sulfate B and a vaccine agent containing chondroitin sulfate B, wherein chondroitin sulfate B is used as an adjuvant in a vaccine, that is, 5 to 105 μg of chondroitin sulfate B is contained in each single vaccine dose. Chondroitin sulfate B as a vaccine adjuvant, toxic side effects, in the immune dose range is safe and reliable, can effectively induce antigen-specific humoral immune response, and the induced humoral immune response effect is better than the adjuvant group, chondroitin sulfate B performance is stable, high biological potency, no toxic effect, can be added to a variety of traditional vaccines and genetic engineering vaccines as vaccine adjuvants.