643-79-8
1,2-Phthalic dicarboxaldehyde
CAS: 643-79-8
Molecular Formula: C8H6O2
643-79-8 - Names and Identifiers
| Name | 1,2-Phthalic dicarboxaldehyde |
| Synonyms | OPA phthalaldehyde O-PHTALALDEHYDE o-phthaladehyde Phthaldialdehyde O-PHTHALALDEHYDE o-Phthaldialdehyde 1,2-Benzenedialdehyde o-Phthaldialdehyde OPD o-Phthalaldehyde (1.11452) benzene-1,2-dicarbaldehyde o-Phthalic dicarboxaldehyde Benzene-1,2-dicarboxaldehyde 1,2-Phthalic dicarboxaldehyde |
| CAS | 643-79-8 |
| EINECS | 211-402-2 |
| InChI | InChI=1/C8H6O2/c9-5-7-3-1-2-4-8(7)6-10/h1-6H |
643-79-8 - Physico-chemical Properties
| Molecular Formula | C8H6O2 |
| Molar Mass | 134.13 |
| Density | 1.189g/cm3 |
| Melting Point | 54-57℃ |
| Boling Point | 266.1°C at 760 mmHg |
| Flash Point | 98.5°C |
| Water Solubility | soluble |
| Solubility | Soluble in water, ethanol, ether and organic solvents, slightly soluble in petroleum ether. |
| Vapor Presure | 0.0088mmHg at 25°C |
| Appearance | Light yellow crystalline powder |
| Storage Condition | 2-8 ℃, dark |
| Sensitive | `sensitive` to air, light and humidity |
| Refractive Index | 1.622 |
| MDL | MFCD00003335 |
| Physical and Chemical Properties | Density 1.13 melting point 54-57°C boiling point 83-84°C (0.7501 mmHg) flash point 132°C water-soluble solution |
| Use | Mainly used in medicine, dyes, etc |
643-79-8 - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R25 - Toxic if swallowed R34 - Causes burns R43 - May cause sensitization by skin contact |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN2923 8/PG 2 |
643-79-8 - Upstream Downstream Industry
643-79-8 - Reference
| Reference Show more | 1. Luo Yuting, Wu, Bao-Sen Valley, the sea, etc. Characteristics and antioxidant activity of crude peptides from Norton fire legs in different processing years [J]. Meat Research 2017(09):32-37. 2. Ding Fan, Liu, Qing, Hua Wang, Quan Jie. Preparation of low-ash industrial protein powder and its paper sizing performance [J]. China leather 2020 49(05):7-15. 3. Zhang Sirui, Guo Aohuan, Han Ying, GE Shuhua, Wang Jian, Xu Zihao. Study on preparation of peptide calcium phosphate from waste protein [J]. Leather and chemical industry, 2019, 36(04):9-13. 4. Wang Mingying, GE Shuhua, Yuan Yan, et al. Study on the preparation process of different molecular weight peptide-Zn chelate by leather waste [J]. Leather and Chemical Industry 2020 v.37;No.189(01):7-14 34. 5. GE Shuhua, Yu Yujun, et al. Study on preparation of peptide Ca chelate from leather waste [J]. Soil Bulletin 2019 v.50;No.300(03):206-214. 6. Luo Yanhua, Chen Pei, Hai Wang, Quan Jie. Study on preparation of N-oleoyl compound polypeptide surfactant from Chrome-containing leather shavings [J]. Leather and chemical industry 2017(4). 7. Liu rongmeitian, Yuan Yuan, Geng Qi, et al. Isolation, identification and functional study of lactic acid bacteria from Sichuan Daicheng traditional cheese [J]. China test 2017v.43;No.233(12):58-62. 8. Chen Peiyun, Wang Xianyou, Zhilei Zhao, et al. Identification of Gynostemma pentaphyllum from different habitats by HPLC fingerprint of amino acids [J]. Food Research and Development, 2015(12):94-98. 9. Chen Peiyun, Gong Dongjun, Zhao Zhilei, et al. Study on fingerprint of amino acids in Gynostemma pentaphyllum from Pingli, Shaanxi province [J]. Science and Technology of food industry, 2014, 035(006):67-72. 10. Luo Yanhua, Wang Quanjie, Chen Peihai, et al. Determination of degree of hydrolysis of protein hydrolysates [J]. Leather and chemical industry, 2017, 02:32-37. 11. Wu Baosen, Gu Dahai, Wang Guiying, et al. Antioxidant activity and sodium nitrite scavenging activity of crude peptide from Norton fire leg [J]. Meat Research, 2017, 31(008):6-11. 12. Luo Yanhua, Wang, Quan Jie, Chen Peihai. Comparison of the effect of CaO and NaOH on the hydrolysis of Chrome shavings [J]. Leather and chemical industry 2017 034(003):1-12. 13. Ding Fan, Ji Xiang-hui, Duan Bao-rong, Wang Quan-Jie. Study on preparation of industrial protein powder from waste Chrome shavings [J]. Leather chemical industry, 2020,37(05):10-15 20. 14. Huang, Yanming. Study on degradation mechanism and texture protection of Procambarus clarkii at high temperature [D]. Hubei University of Technology, 2020. 15. Xu Xikai, Xin Jiaying, Ren Jiaxin, Han Ye, Wang Guangjiao, Cui Tianyu. Preparation and physicochemical properties of soluble dietary fiber from wheat bran fermented by Neurospora [J]. Science and Technology of food industry, 2021,42(02):170-176 191.[6] ji xin, Liu Xiao-Qian, Gao Lu, Xiao Su-ping, Liang Yao-hua, Li Chun, Wang Zhi-min. Qualitative and Quantitative Analysis of triterpenoids in fructus Ligustri Lucidi [J]. Chinese Journal of Traditional Chinese Medicine, 2021,46(05):1168-1178. 16. [IF = 3.067] Xiaoyu Wen et al."Transglutaminase induced gels using bitter apricot kernel protein: Chemical, textural and release properties."Food Biosci. 2018 Dec;26:15 17. [IF=4.952] Feng Xue et al."Prevention of frozen-dough from deterioration with incorporation of glutenin-polyphenols conjugates prepared by ultrasound."Lwt Food Sci Technol. 2021 Nov;151:112141 18. [IF=2.659] G.Y. Xiong et al."Process optimization and the relationship between the reaction degree and the antioxidant activity of Maillard reaction products of chicken liver protein hydrolysates."Poultry Sci. 2020 Jul;99:3733 19. [IF=1.984] Guanhao Bu et al."Functional characteristics and structural properties of soybean protein isolate-maltose conjugates."Cereal Chemistry. 2021 May 30 20. [IF=4.952] Xiao Jia et al."Glycation of rice protein and d-xylose pretreated through hydrothermal cooking-assisted high hydrostatic pressure: Focus on the structural and functional properties."Lwt Food Sci Technol. 2022 Apr;160:113194 21. [IF=6.576] Jin Wang et al."Effect of Frying Process on Nutritional Property, Physicochemical Quality, and in vitro Digestibility of Commercial Instant Noodles."Front Nutr. 2022; 9: 823432 22. [IF=5.396] Ge Ge et al."Green tea polyphenols bind to soy proteins and decrease the activity of soybean trypsin inhibitors (STIs) in heated soymilk."Food & Function. 2022 May ;: |
643-79-8 - Introduction
1, chemical field analysis reagents: as amine alkaloid reagents, used for fluorescence determination of primary amines and peptide bond decomposition products. 2. Organic synthesis: It is also a pharmaceutical intermediate. 3. Fluorescent reagent, used for pre-column HPLC separation of amino acid derivatives, flow cytometry to measure the thiol groups of proteins.
Last Update：2022-10-16 17:27:41
643-79-8 - Security information
| WGK Germany | 3 |
| RTECS number | TH6950000 |
| F | 1-8-10 |
| auto-ignition temperature | 480 °C |
| Hazard Note | Irritant/Air Sensitive |
| TSCA | Yes |
| HazardClass | 8 |
| PackingGroup | Ⅱ |
| customs code | 29122900 |
| toxic substance data | 643-79-8(Hazardous Substances Data) |
| Toxicity | LD50 orally in Rabbit: 178 mg/kg LD50 dermal Rat > 2000 mg/kg |
Last Update：2024-04-10 22:29:15
643-79-8 - Nature
| storage conditions | 2-8°C |
| solubility | The solubility of o-phthalaldehyde is 3g/100 mL diisopropyl ether, 5g/100mL deionized water, 20g/100mL chloroform, or 20g/100mL acetone at 20°C. |
| morphology | powder |
| color | yellow |
| PH value | 7 (53g/l, H2O, 20℃) |
| water solubility | soluble |
| sensitivity | Air Sensitive |
| Merck | 14,7368 |
| BRN | 878317 |
| stability | Stable. Air sensitive. Incompatible with strong oxidizing agents, strong bases. |
| InChIKey | ZWLUXSQADUDCSB-UHFFFAOYSA-N |
| NIST chemical information | O-phthalaldehyde(643-79-8) |
| EPA chemical information | 1,2-Benzenedicarboxaldehyde (643-79-8) |
Last Update：2024-04-09 20:52:54
643-79-8 - Uses and synthesis methods
Chemical properties
Yellow needle crystals. Melting point 54-56 ℃.
Uses
1. This product is a pharmaceutical intermediate. It is the latest external efficient and safe antibacterial disinfectant. It is used as a disinfection and sterilization of endoscopic surgical instruments in hospitals. It can be used to synthesize a new anti-platelet aggregation drug indolebofen. It is also an analytical reagent in the chemical field.
3, yellow needle crystal, mainly used in medicine, dyes, etc. Amino acid derivative reagent, fluorescence detection, the reaction can be completed in one minute, but the product is unstable and needs to be detected immediately.
4, mainly used in medicine, dyes, amino acid derivative reagents, etc.
5, amine alkaloid reagents, used for fluorescence determination of primary amines and peptide bond decomposition products. Organic synthesis.?
6. Reagents for amine alkaloids, used for fluorescence determination of primary amines and peptide bond decomposers; suitable for pre-column derivatization of amino acids in high performance liquid chromatography separation; used for measurement of protein sulfhydryl by flow cytometry
7, 1 chemical field analysis reagent: as an amine alkaloid reagent, used for fluorescence determination of primary amines and peptide bond decomposition products. 2. Organic synthesis: It is also a pharmaceutical intermediate 3. Fluorescent reagent, used for pre-column HPLC separation of amino acid derivatives, flow cytometry to measure the thiol groups of proteins.
8, for medical inspection
Last Update：2024-04-09 19:04:55
Supplier List
Featured ProductsSpot supply
Product Name: Phthaldialdehyde Reagent Visit Supplier Webpage Request for quotationCAS: 643-79-8
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: o-Phthalaldehyde Request for quotationCAS: 643-79-8
Tel: 15335994747
Email: 3521670276@qq.com
Mobile: 15335994747
QQ: 3521670276
Spot supply
Product Name: 1,2-Phthalic dicarboxaldehyde Request for quotationCAS: 643-79-8
Tel: 0086 15028179902
Email: sales@hbmojin.com
Mobile: 0086 15028179902
QQ: 2632046152
Wechat: 0086 15028179902
WhatsApp: 0086 15028179902
Multiple SpecificationsSpot supply
Product Name: Phthalaldehyde Visit Supplier Webpage Request for quotationCAS: 643-79-8
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Product Name: 1,2-Phthalic dicarboxaldehyde Request for quotation
CAS: 643-79-8
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CAS: 643-79-8
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: 1,2-Phthalic dicarboxaldehyde Request for quotationCAS: 643-79-8
Tel: +86-17505207175
Email: r@reformchem.com
Mobile: +86-17505207175
QQ: 3787852685
Wechat: chemical6666
Spot supply
Product Name: 1,2-Phthalic dicarboxaldehyde Request for quotationCAS: 643-79-8
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Wechat: chemical6666
Product Name: o-Phthalaldehyde Request for quotation
CAS: 643-79-8
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
CAS: 643-79-8
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Multiple Specifications
Product Name: o-Phthalaldehyde Request for quotationCAS: 643-79-8
Tel: 86-10-10086 81625225
Email: yeqim@boyechemicals.com
Mobile: 86-15387090420
QQ: 1377812380
Spot supply
Product Name: o-Phthalaldehyde Visit Supplier Webpage Request for quotationCAS: 643-79-8
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Featured ProductsSpot supply
Product Name: Phthaldialdehyde Reagent Visit Supplier Webpage Request for quotationCAS: 643-79-8
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: o-Phthalaldehyde Request for quotationCAS: 643-79-8
Tel: 15335994747
Email: 3521670276@qq.com
Mobile: 15335994747
QQ: 3521670276
Spot supply
Product Name: 1,2-Phthalic dicarboxaldehyde Request for quotationCAS: 643-79-8
Tel: 0086 15028179902
Email: sales@hbmojin.com
Mobile: 0086 15028179902
QQ: 2632046152
Wechat: 0086 15028179902
WhatsApp: 0086 15028179902
Multiple SpecificationsSpot supply
Product Name: Phthalaldehyde Visit Supplier Webpage Request for quotationCAS: 643-79-8
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Product Name: 1,2-Phthalic dicarboxaldehyde Request for quotation
CAS: 643-79-8
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CAS: 643-79-8
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: 1,2-Phthalic dicarboxaldehyde Request for quotationCAS: 643-79-8
Tel: +86-17505207175
Email: r@reformchem.com
Mobile: +86-17505207175
QQ: 3787852685
Wechat: chemical6666
Spot supply
Product Name: 1,2-Phthalic dicarboxaldehyde Request for quotationCAS: 643-79-8
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Wechat: chemical6666
Product Name: o-Phthalaldehyde Request for quotation
CAS: 643-79-8
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
CAS: 643-79-8
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Multiple Specifications
Product Name: o-Phthalaldehyde Request for quotationCAS: 643-79-8
Tel: 86-10-10086 81625225
Email: yeqim@boyechemicals.com
Mobile: 86-15387090420
QQ: 1377812380
Spot supply
Product Name: o-Phthalaldehyde Visit Supplier Webpage Request for quotationCAS: 643-79-8
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
View History
Downstream Products for 643-79-8
Pentacene
Lacidipine
NAPHTHALENE-2,3-DICARBOXALDEHYDE
2H-Isoindole
2,3-NAPHTHALENEDICARBOXYLIC ACID DIMETHYL ESTER
PHTHALAMIDE
DIBENZYL PHTHALATE
Methyl 3-isoquinolinecarboxylate
Lacidipine
NAPHTHALENE-2,3-DICARBOXALDEHYDE
2H-Isoindole
2,3-NAPHTHALENEDICARBOXYLIC ACID DIMETHYL ESTER
PHTHALAMIDE
DIBENZYL PHTHALATE
Methyl 3-isoquinolinecarboxylate