2H-Isoindole - Names and Identifiers
2H-Isoindole - Physico-chemical Properties
| Molecular Formula | C8H7N
|
| Molar Mass | 117.15 |
| Density | 1.149±0.06 g/cm3(Predicted) |
| Melting Point | 149.5-150 °C |
| Boling Point | 275.4±9.0 °C(Predicted) |
| pKa | 17.00±0.30(Predicted) |
2H-Isoindole - Upstream Downstream Industry
| Raw Materials | 2H-Isoindole, 2-(1,1-dimethylethyl)-
6,11-Imino-5,12-methanonaphtho[2,3-g]phthalazine, 5,5a,6,11,11a,12-hexahydro-1,4-di-2-pyridinyl-, (5R,5aR,6R,11S,11aS,12S)-rel-
2-(prop-2-yn-1-yl)-2,3-dihydro-1H-isoindole
1,2-Bis(bromomethyl)benzene
AKOS AUF2082
1,2,3,4-tetrahydro-naphthalen-1,4-imine
o-Phthalaldehyde
|
| Downstream Products | Isoindoline
|
2H-Isoindole - Introduction
2H-Isoindole (2H-Isoindole) is an organic compound with the chemical formula C8H7N. It is an organic ring compound containing an isoindole skeleton.
Nature:
2H-Isoindole is a colorless or light yellow crystal with a special odor. It is a solid at room temperature, soluble in organic solvents (such as ethanol, dimethyl sulfoxide, etc.), insoluble in water. 2H-Isoindole has strong aromatic properties.
Use:
2H-Isoindole is often used in organic synthesis to prepare a variety of organic compounds, such as synthetic organic dyes, photoelectric materials, functional molecules, etc. It can also be used as a fluorescent probe for biomedical research.
Method:
Generally, the preparation of 2H-Isoindole can be achieved by a cyclization reaction catalyzed by a transition metal catalyst of an appropriate ligand. For example, the cyclization reaction can be carried out by bringing an aromatic isonitrile having an appropriate substituent and an organic reducing agent in the presence of a suitable catalyst.
Safety Information:
The toxicity and risk data of 2H-Isoindole are less reported. Therefore, when using or handling 2H-Isoindole, it is necessary to take appropriate protective measures, such as wearing chemical protective gloves and goggles, and ensure that it is operated under well-ventilated conditions. When handling this compound, avoid inhalation of its dust or contact with skin, eyes or ingestion. If contact occurs, rinse immediately with plenty of water and seek medical attention if necessary. In addition, since long-term exposure and inhalation of this compound may be harmful to health, it is recommended to significantly reduce its concentration and contact time when using 2H-Isoindole. It is best to store it in a cool, dry place and in isolation from other chemicals.
Last Update：2024-04-10 22:29:15