6-氨基-5-氯嘧啶-4-羧酸
6-Amino-5-chloro-4-pyrimidinecarboxylicacid
CAS: 914916-98-6
Molecular Formula: C5H4ClN3O2
6-氨基-5-氯嘧啶-4-羧酸 - Names and Identifiers
6-氨基-5-氯嘧啶-4-羧酸 - Physico-chemical Properties
| Molecular Formula | C5H4ClN3O2 |
| Molar Mass | 173.56 |
| Density | 1.690 |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
6-氨基-5-氯嘧啶-4-羧酸 - Introduction
It is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline powder.
-Solubility: slightly soluble in water, soluble in acid and alkali solution.
-Melting point: approximately 292-296°C.
Use:
-is an important intermediate compound that can be used to synthesize pesticides, drugs, dyes and other organic compounds.
-It can be used as a raw material for the synthesis of pyrimidine compounds and participate in the construction of pyrimidine rings.
Method:
It can be synthesized by the following steps:
1. Aminopyrimidine reacts with chloroacetic acid under alkaline conditions to generate 6-chloro-5-aminopyrimidine.
2. then the 6-chloro -5-amino pyrimidine and carbamic acid reaction, removal of chlorine atoms, generation of 6-amino -5-chloropyrimidine.
3. Finally, 6-amino -5-chloropyrimidine is reacted with carbon dioxide under alkaline conditions to form a pyridine.
Safety Information:
-Toxicity information is limited, but should be considered toxic chemicals and handled in accordance with laboratory safety practices.
-When using chemicals or participating in the synthesis process, wear appropriate protective equipment, such as laboratory gloves and goggles, to avoid contact with skin and eyes.
-in the storage and handling of chemicals, should pay attention to the measures of fire and explosion prevention.
-If ingested or inhaled, seek medical help immediately and provide information about the chemical to your doctor.
Nature:
-Appearance: White crystalline powder.
-Solubility: slightly soluble in water, soluble in acid and alkali solution.
-Melting point: approximately 292-296°C.
Use:
-is an important intermediate compound that can be used to synthesize pesticides, drugs, dyes and other organic compounds.
-It can be used as a raw material for the synthesis of pyrimidine compounds and participate in the construction of pyrimidine rings.
Method:
It can be synthesized by the following steps:
1. Aminopyrimidine reacts with chloroacetic acid under alkaline conditions to generate 6-chloro-5-aminopyrimidine.
2. then the 6-chloro -5-amino pyrimidine and carbamic acid reaction, removal of chlorine atoms, generation of 6-amino -5-chloropyrimidine.
3. Finally, 6-amino -5-chloropyrimidine is reacted with carbon dioxide under alkaline conditions to form a pyridine.
Safety Information:
-Toxicity information is limited, but should be considered toxic chemicals and handled in accordance with laboratory safety practices.
-When using chemicals or participating in the synthesis process, wear appropriate protective equipment, such as laboratory gloves and goggles, to avoid contact with skin and eyes.
-in the storage and handling of chemicals, should pay attention to the measures of fire and explosion prevention.
-If ingested or inhaled, seek medical help immediately and provide information about the chemical to your doctor.
Last Update：2024-04-09 21:00:56
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View History
6-氨基-5-氯嘧啶-4-羧酸
Tri-t-butylphosphosphin
5-(2-AMINO-ETHYL)-2-METHOXY-PHENOL HYDROCHLORIDE
二苄基(氮杂二基双(乙烷-2,1-二基))二氨基甲酸酯
4 B-4 2-[2-(4-氟苯基)-2-氧代-1-苯基乙基]-4-甲基-3-氧代-N-苯基戊酰胺
柠檬酸铁铵(易潮解)
乙酰丙酮钯(II)
5-叔丁基-2-甲氧基苯甲酸
beta-Oxo-4-morpholinepropanoic acid ethyl ester
Tri-t-butylphosphosphin
5-(2-AMINO-ETHYL)-2-METHOXY-PHENOL HYDROCHLORIDE
二苄基(氮杂二基双(乙烷-2,1-二基))二氨基甲酸酯
4 B-4 2-[2-(4-氟苯基)-2-氧代-1-苯基乙基]-4-甲基-3-氧代-N-苯基戊酰胺
柠檬酸铁铵(易潮解)
乙酰丙酮钯(II)
5-叔丁基-2-甲氧基苯甲酸
beta-Oxo-4-morpholinepropanoic acid ethyl ester