It is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline powder.
-Solubility: slightly soluble in water, soluble in acid and alkali solution.
-Melting point: approximately 292-296°C.
Use:
-is an important intermediate compound that can be used to synthesize pesticides, drugs, dyes and other organic compounds.
-It can be used as a raw material for the synthesis of pyrimidine compounds and participate in the construction of pyrimidine rings.
Method:
It can be synthesized by the following steps:
1. Aminopyrimidine reacts with chloroacetic acid under alkaline conditions to generate 6-chloro-5-aminopyrimidine.
2. then the 6-chloro -5-amino pyrimidine and carbamic acid reaction, removal of chlorine atoms, generation of 6-amino -5-chloropyrimidine.
3. Finally, 6-amino -5-chloropyrimidine is reacted with carbon dioxide under alkaline conditions to form a pyridine.
Safety Information:
-Toxicity information is limited, but should be considered toxic chemicals and handled in accordance with laboratory safety practices.
-When using chemicals or participating in the synthesis process, wear appropriate protective equipment, such as laboratory gloves and goggles, to avoid contact with skin and eyes.
-in the storage and handling of chemicals, should pay attention to the measures of fire and explosion prevention.
-If ingested or inhaled, seek medical help immediately and provide information about the chemical to your doctor.