Molecular Formula | C21H20O10 |
Molar Mass | 432.38 |
Density | 1.70±0.1 g/cm3(Predicted) |
Melting Point | 172-174 °C (decomp)(Solv: water (7732-18-5)) |
Boling Point | 765.6±60.0 °C(Predicted) |
Appearance | Yellow |
pKa | 6.20±0.40(Predicted) |
Storage Condition | Sealed in dry,Store in freezer, under -20°C |
Reference Show more | 1. [IF=2.19] Yawei Zhang et al."Effects of high temperature steam treatment on microbial and phytochemical contents, antioxidant activities, chemical stability, and shelf life of oral liquid prepared from the leaves of Zanthoxylum bungeanum Maxim."J Food Process Pres. 2. [IF=3.978] Yunbin Lyu et al."Identification and characterization of three flavonoid 3-O-glycosyltransferases from Epimedium koreanum Nakai."Biochem Eng J. 2020 Nov;163:107759 3. [IF=2.633] Yanni Cao et al."Seasonal Variation in Phenolic Compounds and Antioxidant Activity in Leaves of Cyclocarya paliurus (Batal.) Iljinskaja."Forests. 2019 Aug;10(8):624 4. [IF=2.431] Su Shang et al."Diversity of red, green and black cultivars of Chinese Toon [Toona sinensis (A. Juss.) Roem]: anthocyanins, flavonols and antioxidant activity."J Food Meas Charact. 2020 Dec;14(6):3206-3215 5. [IF=2.19] Sheng-xiang Yang et al."Extraction of flavonoids from Cyclocarya paliurus (Juglandaceae) leaves using ethanol/salt aqueous two-phase system coupled with ultrasonic."J Food Process Pres. 2020 Jun;44(6):e14469 |
biological activity | Afzelin (Kaempferol-3-O-rhamnoside) is a flavonol glycoside found in Houttuynia cordata, widely used in the preparation of antibacterial, antipyretic, antidote and anti-inflammatory agents. Afzelin attenuates mitochondrial damage, enhances mitochondrial biosynthesis, and reduces levels of mitochondria-associated proteins, Parkinson's disease and PTEN-induced putative kinase 1. Afzelin increased survival in mice treated with D-galactosamine (GalN)/LPS and decreased serum levels of alanine aminotransferase and pro-inflammatory cytokines. |