461-06-3
carnitine
CAS: 461-06-3;406-76-8
Molecular Formula: C7H15NO3
461-06-3 - Names and Identifiers
| Name | carnitine |
| Synonyms | CARNITIN carnitine Carnitina DL-Carnitine CARNITINE CHLORIDE, DL-(RG) -Hydroxy-butyrotrimethylbetaine 3-hydroxy-4-(trimethylammonio)butanoate；Novain |
| CAS | 461-06-3 406-76-8 |
| EINECS | 206-976-6 |
| InChI | InChI=1/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3 |
461-06-3 - Physico-chemical Properties
| Molecular Formula | C7H15NO3 |
| Molar Mass | 161.199 |
| Physical and Chemical Properties | Chemical properties A mixture of left-handed and right-handed bodies. The mixer is a hygroscopic crystalline solid with a melting point of 195-197 ℃ (decomposition). L-Spin ([541-15-1]), also known as vitamin BT, is a crystal, which is one of the components that make up striated muscle and liver. Its melting point is 196-198 ℃ (decomposition). The right-handed body ([541-14-0]) is also a crystal with a melting point of 210-212°C (decomposition). Carnitine is soluble in water and hot ethanol, slightly soluble in cold ethanol, insoluble in acetone and ether. This product is generally prepared as hydrochloride. |
| Use | Uses L-carnitine can promote the decomposition of fat, plays an important role in the metabolism of long chain fatty acids. It is also used as a sports nutrition agent to improve the body's energy, endurance and energy during strenuous exercise, compensate for the loss of the body when exhausted, and increase the resistance to fatigue, effective and rapid recovery of physical strength. Carnitine is an appetite-promoting drug, which can stimulate appetite, regulate gastrointestinal function, promote the secretion of digestive juice and enhance the activity of digestive enzymes. For the treatment of indigestion, loss of appetite, chronic gastritis and abdominal distension, heating, etc. It is also used for the treatment of elderly digestive dysfunction, gastrointestinal disorders caused by pregnancy, infantile anorexia and anorexia. The product should not be mixed with alkaline drugs |
461-06-3 - Upstream Downstream Industry
461-06-3 - Production method
there are two methods. 1. The epichlorohydrin method reacts from epichlorohydrin and trimethylamine to form a quaternary ammonium salt to prepare 3-chloro-2-hydroxypropyltrimethylamine chloride, which is then cyanated to 3-cyano-2-hydroxypropyltrimethylamine chloride, and finally hydrolyzed with concentrated hydrochloric acid to obtain carnitine hydrochloride. The route of this method is short and the yield is high. The reaction yield of quaternary amine salt is 91.5%, cyanidation reaction yield is 93.4%, hydrolysis reaction yield is 86%, and the product is easy to refine. The epichlorohydrin method can also adopt the process of cyanidation first, then quaternary ammonium salt, and finally hydrolysis, but the cyanidation reaction uses hydrocyanic acid, which is not easy to control, and it is not safe, and the yield is also low. 2. Ethyl bromoacetoacetate method uses & gamma; ethyl bromoacetoacetate as raw material, first reduced to & gamma with sodium tetrahydroborate;-ethyl bromoβ-hydroxybutyrate, and then reacted with trimethylamine to form a quaternary ammonium salt to obtain trimethylamine bromo-β-hydroxybutyrate ethyl ester, and finally hydrolyzed with hydrochloric acid to form carnitine hydrochloride. The raw materials of this method are easy to obtain and the process equipment requirements are general, but the reducing agent is expensive and the yield is low. The reduction yield is 50%, and the two-step yield of quaternary ammonium salt and hydrolysis is 30%.
Last Update：2024-04-10 22:29:15
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Product Name: DL-Carnitine Visit Supplier Webpage Request for quotationCAS: 406-76-8
Tel: 609-228-6898
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tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: (R)-3-HYDROXY-4-(TRIMETHYLAMMONIO)BUTYRATE Visit Supplier Webpage Request for quotationCAS: 461-06-3
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
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Product Name: DL-Carnitine Visit Supplier Webpage Request for quotationCAS: 461-06-3
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Multiple SpecificationsSpot supply
Product Name: DL-Carnitine Visit Supplier Webpage Request for quotationCAS: 461-06-3
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
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View History
461-06-3
2-(1-NAPHTHYL)PYRIDO[1,2-A]PYRIMIDIN-5-IUM PERCHLORATE
Quinoline, 4-chloro-7-iodo-6-methoxy-
Pigment Blue 1
1,4-二氮杂环庚烷-1-甲酸叔丁酯&1-BOC-高哌嗪
H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,6-dihydro-1-methyl-5-[5-[(4-phenyl-1-piperazinyl)carbonyl]-2-propoxyphenyl]-3-propyl-
Phosphonodithioic acid, [2-(ethylthio)vinyl]-, O-ethyl S-[(ethylthio)methyl] ester (6CI,7CI,8CI)
4-Fluoro-3-methoxy-5-methylphenylboronic acid pinacol ester
9Z,12Z-OCTADECADIENOIC-9,10,12,13-D4 ACID
匙羹藤苷元
2-(1-NAPHTHYL)PYRIDO[1,2-A]PYRIMIDIN-5-IUM PERCHLORATE
Quinoline, 4-chloro-7-iodo-6-methoxy-
Pigment Blue 1
1,4-二氮杂环庚烷-1-甲酸叔丁酯&1-BOC-高哌嗪
H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,6-dihydro-1-methyl-5-[5-[(4-phenyl-1-piperazinyl)carbonyl]-2-propoxyphenyl]-3-propyl-
Phosphonodithioic acid, [2-(ethylthio)vinyl]-, O-ethyl S-[(ethylthio)methyl] ester (6CI,7CI,8CI)
4-Fluoro-3-methoxy-5-methylphenylboronic acid pinacol ester
9Z,12Z-OCTADECADIENOIC-9,10,12,13-D4 ACID
匙羹藤苷元
Raw Materials for 461-06-3
Ethyl acetoacetate
Trimethylamine
Ethyl butyrate
Acetyl bromide
Hydrochloric acid
[(±)-(4-amino-2-hydroxy-4-oxobutyl)trimethylammonium] chloride
DL-Carnitine hydrochloride
Dimethyl sulfate
Trimethylamine
Ethyl butyrate
Acetyl bromide
Hydrochloric acid
[(±)-(4-amino-2-hydroxy-4-oxobutyl)trimethylammonium] chloride
DL-Carnitine hydrochloride
Dimethyl sulfate
Downstream Products for 461-06-3