4-Fluoro-3-Amino-Acetophenone
3'-amino-4'-fluoroacetophenone
CAS: 2002-82-6
Molecular Formula: C8H8FNO
4-Fluoro-3-Amino-Acetophenone - Names and Identifiers
| Name | 3'-amino-4'-fluoroacetophenone |
| Synonyms | 3'-Amino-4'-f 3-amino-4-fluoroacetophenone 4-FLUORO-3-AMINO-ACETOPHENONE 4-fluoro-3-amino-acetophenone 4-Acetyl-2-aminofluorobenzene 3'-amino-4'-fluoroacetophenone 1-(3-amino-4-fluorophenyl)ethanone 4'-fluoro-3'-aminoacetophenone,1-(3-amino-4-fluorophenyl)ethanone |
| CAS | 2002-82-6 |
| InChI | InChI=1/C8H8FNO/c1-5(11)6-2-3-7(9)8(10)4-6/h2-4H,10H2,1H3 |
4-Fluoro-3-Amino-Acetophenone - Physico-chemical Properties
| Molecular Formula | C8H8FNO |
| Molar Mass | 153.15 |
| Density | 1.201 |
| Melting Point | 70-72℃ |
| Boling Point | 290℃ |
| Flash Point | 129℃ |
| Vapor Presure | 0.002mmHg at 25°C |
| Appearance | Solid |
| Maximum wavelength(λmax) | 326nm(MeOH)(lit.) |
| pKa | 2.02±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.548 |
| MDL | MFCD00115400 |
4-Fluoro-3-Amino-Acetophenone - Introduction
3 '-amino-4'-fluoroacetophenone is an organic compound with the chemical formula C8H8FNO. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless solid
-Melting Point: about 100-102 ℃
-Boiling point: About 275 ℃
-Solubility: Soluble in organic solvents such as ether, dichloromethane and alcohols, insoluble in water.
Use:
3 '-amino-4'-fluoroacetophenone is an intermediate in the synthesis of drugs and organic synthetic compounds, and is commonly used in the preparation of biologically active organic molecules, such as drugs, pesticides and dyes.
Method:
The preparation method of 3 '-amino-4'-fluoroacetophenone can be carried out by the following steps:
1. Phenylacetyl fluoride (C8H7COF) reacts with carbamone (CH3C(O)NH2) to generate 3 '-amino-4'-fluoroacetophenone in the presence of a base.
Safety Information:
The safety of 3 '-amino-4'-fluoroacetophenone is not fully understood, so the following matters need to be paid attention to when using and handling:
-This compound may be irritating to the skin, eyes and respiratory tract. Avoid contact.
-Wear appropriate protective equipment, such as gloves and goggles, when in use.
-During operation, please ensure that good ventilation conditions are provided and avoid inhaling the vapor of this compound.
-If it is accidental contact or inhalation, please immediately flush the affected area with plenty of water and seek medical assistance.
When using 3 '-amino-4'-fluoroacetophenone, it is recommended to follow the safe operation specifications and use it when you are familiar with the properties and risks of the chemical substances. Also, comply with local regulations and requirements when storing and disposing of this compound.
Nature:
-Appearance: Colorless solid
-Melting Point: about 100-102 ℃
-Boiling point: About 275 ℃
-Solubility: Soluble in organic solvents such as ether, dichloromethane and alcohols, insoluble in water.
Use:
3 '-amino-4'-fluoroacetophenone is an intermediate in the synthesis of drugs and organic synthetic compounds, and is commonly used in the preparation of biologically active organic molecules, such as drugs, pesticides and dyes.
Method:
The preparation method of 3 '-amino-4'-fluoroacetophenone can be carried out by the following steps:
1. Phenylacetyl fluoride (C8H7COF) reacts with carbamone (CH3C(O)NH2) to generate 3 '-amino-4'-fluoroacetophenone in the presence of a base.
Safety Information:
The safety of 3 '-amino-4'-fluoroacetophenone is not fully understood, so the following matters need to be paid attention to when using and handling:
-This compound may be irritating to the skin, eyes and respiratory tract. Avoid contact.
-Wear appropriate protective equipment, such as gloves and goggles, when in use.
-During operation, please ensure that good ventilation conditions are provided and avoid inhaling the vapor of this compound.
-If it is accidental contact or inhalation, please immediately flush the affected area with plenty of water and seek medical assistance.
When using 3 '-amino-4'-fluoroacetophenone, it is recommended to follow the safe operation specifications and use it when you are familiar with the properties and risks of the chemical substances. Also, comply with local regulations and requirements when storing and disposing of this compound.
Last Update：2024-04-09 20:52:54
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CAS: 2002-82-6
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View History
4-Fluoro-3-Amino-Acetophenone
2-(氯甲基)-2-(羟甲基)吡咯烷-1-羧酸叔丁酯
灵芝(红芝)
2-(2-nitrophenoxy)-N-[4-(prop-2-en-1-yloxy)phenyl]propanamide
甲醇中脱落酸标准溶液
Phenol, 4-ethoxy-, 1-formate
ORTHO-NORNUCIFERINE
4-Fluorophenyl methyl sulphide
3-BroMo-2-dichloroMethyl-6-Methyl-iMidazo[1,2-a]pyridine hydrobroMide
3,4-二羟基苯甲酸单钾盐
2-(氯甲基)-2-(羟甲基)吡咯烷-1-羧酸叔丁酯
灵芝(红芝)
2-(2-nitrophenoxy)-N-[4-(prop-2-en-1-yloxy)phenyl]propanamide
甲醇中脱落酸标准溶液
Phenol, 4-ethoxy-, 1-formate
ORTHO-NORNUCIFERINE
4-Fluorophenyl methyl sulphide
3-BroMo-2-dichloroMethyl-6-Methyl-iMidazo[1,2-a]pyridine hydrobroMide
3,4-二羟基苯甲酸单钾盐