ORTHO-NORNUCIFERINE
ORTHO-NORNUCIFERINE
CAS: 3153-55-7
Molecular Formula: C18H19NO2
ORTHO-NORNUCIFERINE - Names and Identifiers
ORTHO-NORNUCIFERINE - Physico-chemical Properties
| Molecular Formula | C18H19NO2 |
| Molar Mass | 281.35 |
| Density | 1.216±0.06 g/cm3(Predicted) |
| Melting Point | 195-197℃ (ethyl acetate ) |
| Boling Point | 451.4±45.0 °C(Predicted) |
| pKa | 10.12±0.20(Predicted) |
| Storage Condition | 2-8℃ |
| In vitro study | O-Nornuciferine has an IC 50 of 7.91 μM in vitro hERG blockages measured in HEK293 cells. O-Nornuciferine (100 μM) has 47% hERG channel inhibition in Xenopus oocytes by lotus alkaloids. |
ORTHO-NORNUCIFERINE - Reference
| Reference Show more | 1. [IF=5.279] Xianbao Deng et al."Analysis of Isoquinoline Alkaloid Composition and Wound-Induced Variation in Nelumbo Using HPLC-MS/MS."J Agr Food Chem. 2016;64(5):1130–1136 2. [IF=4.032] Qiu-yue Xiao et al."A network pharmacology-based study on key pharmacological pathways and targets of Qi Fu Yin acting on Alzheimer's disease."Exp Gerontol. 2021 Jul;149:111336 3. [IF=1.902] Yongjing Liu et al."Evaluation of Green and Efficient deep eutectic solvents as media for extracting Alkaloids from Lotus Leaf."Biomedical Chromatography. 2021 Dec 06 |
ORTHO-NORNUCIFERINE - Reference Information
| biological activity | O-Noruciferine is a porphyrin alkaloid of lotus leaf, which is a potent hERG channel inhibitor. |
Last Update：2024-04-10 22:29:15
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View History
ORTHO-NORNUCIFERINE
4-Fluorophenyl methyl sulphide
3-BroMo-2-dichloroMethyl-6-Methyl-iMidazo[1,2-a]pyridine hydrobroMide
3,4-二羟基苯甲酸单钾盐
Einecs 286-151-5
4(3H)-Quinazolinone, 2-[(2-pyridinylthio)methyl]-3-[3-(trifluoromethyl)phenyl]-
Direct Orange 36
epsilan
2-乙基-5-甲基吡嗪
ethyl 2-((4-methoxybenzyl)oxy)acetate
4-Fluorophenyl methyl sulphide
3-BroMo-2-dichloroMethyl-6-Methyl-iMidazo[1,2-a]pyridine hydrobroMide
3,4-二羟基苯甲酸单钾盐
Einecs 286-151-5
4(3H)-Quinazolinone, 2-[(2-pyridinylthio)methyl]-3-[3-(trifluoromethyl)phenyl]-
Direct Orange 36
epsilan
2-乙基-5-甲基吡嗪
ethyl 2-((4-methoxybenzyl)oxy)acetate