4-(((6-Chloropyridin-3-yl)methyl)(2,2-difluoroethyl)amino)furan-2(5H)-one
Flupyradifurone
CAS: 951659-40-8
Molecular Formula: C12H11ClF2N2O2
4-(((6-Chloropyridin-3-yl)methyl)(2,2-difluoroethyl)amino)furan-2(5H)-one - Names and Identifiers
4-(((6-Chloropyridin-3-yl)methyl)(2,2-difluoroethyl)amino)furan-2(5H)-one - Physico-chemical Properties
| Molecular Formula | C12H11ClF2N2O2 |
| Molar Mass | 288.68 |
| Density | 1.41±0.1 g/cm3(Predicted) |
| Melting Point | 69 - 71°C |
| Boling Point | 457.7±45.0 °C(Predicted) |
| Solubility | DMSO (Slightly, Sonicated), Methanol (Slightly) |
| Appearance | neat |
| Color | White to Pale Brown |
| BRN | 19518067 |
| pKa | 0.22±0.10(Predicted) |
| Storage Condition | Refrigerator |
4-(((6-Chloropyridin-3-yl)methyl)(2,2-difluoroethyl)amino)furan-2(5H)-one - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| WGK Germany | 2 |
4-(((6-Chloropyridin-3-yl)methyl)(2,2-difluoroethyl)amino)furan-2(5H)-one - Reference Information
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Overview | with the withdrawal of highly toxic pesticides in the global market, neonicotinoid insecticides have gradually become the control of spike-sucking pests, the most effective class of insecticides for small lepidopteran and coleopteran pests. In response to the problem of high bee venom of some neonicotinoid insecticides, Bayer Crop Science developed a new type of neonicotinoid insecticide, the medicament can be highly selectively applied to a variety of stinging and sucking mouthpiece pests, with good efficiency and long duration, and has no interactive resistance to conventional neonicotinoid insecticides, its most prominent feature is low toxicity to pollinating insects such as bees. |
| Scope of Application | flupifuranone can be used to control tomato, pepper, potato, cucumber, grape, watermelon, coffee, nuts, citrus and some field crops in aphids, whiteflies, toads, leaf hoppers, Frankliniella occidentalis, leaf flies, flounder, soft musks, citrus wood lice and potato beetle and other pests, it has good internal absorption and conductivity, is effective for all growth stages of larvae, adults and other pests, and has fast efficacy and long duration. |
| mechanism of action | flupirofuranone contains a special pharmacodynamic group butenolide, so it has good internal absorption conductivity, after foliar spraying or seed treatment, it can be quickly transmitted to all parts of the plant, which can effectively control the back of the leaf surface or the hidden feeding pests, and can inhibit the feeding of insects, this in turn reduces the dependence on insect-mediated transmission of pathogens. |
| safety in use | The most prominent advantage of flupirfuranone is its low toxicity to pollinating insects such as bees. Although flupirofuranone still has some effect on bee foraging (on sugar) and cognitive ability at higher doses, the recommended dose of flupirfuranone on bee foraging behavior, foraging bees, young bees and bee colony development of honey bee health, hives and overwintering colonies have no adverse effects, so it is the United States Environmental Protection Agency as a safe candidate for seven types of horticultural crops and cotton cultivation. In addition, flupirofuranone has low toxicity to non-target organisms in the environment, as shown in Table 1. Flupirofuranone has low toxicity to rainbow trout, earthworms, Daphnia, algae, bumblebees and bees, and is moderately toxic to quails. a long-term study on bees showed that the pesticide had no side effects on bees when the dosage of the pesticide was 205 G a. I./hm2 in rape field during the flowering period. |
Last Update：2024-04-09 20:48:19
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View History
4-(((6-Chloropyridin-3-yl)methyl)(2,2-difluoroethyl)amino)furan-2(5H)-one
3H-Pyrrolo[1,2-a]indol-3-one,1,2,9,9a-tetrahydro-9,9-dimethyl-(9CI)
53488-28-1
7-[(4-Aminobenzoyl)amino]-4-hydroxy-2-naphthalenesulfonic acid sodium salt
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1261943-33-2
477888-94-1
2-(3-methoxyphenyl)-2-oxoethyl 6-methyl-2-phenyl-4-quinolinecarboxylate
1-Pentanone, 2-amino-1-(1,1-dioxido-3-thiazolidinyl)-3-methyl-, (2S,3S)-
L-Lysine, glycyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-α-glutamyl-L-α-aspartyl-L-valylglycylglycyl-6-aminohexanoyl-L-lysyl-L-lysyl-L-lysyl-L-lysyl-L-lysyl
3H-Pyrrolo[1,2-a]indol-3-one,1,2,9,9a-tetrahydro-9,9-dimethyl-(9CI)
53488-28-1
7-[(4-Aminobenzoyl)amino]-4-hydroxy-2-naphthalenesulfonic acid sodium salt
73590-58-6
1261943-33-2
477888-94-1
2-(3-methoxyphenyl)-2-oxoethyl 6-methyl-2-phenyl-4-quinolinecarboxylate
1-Pentanone, 2-amino-1-(1,1-dioxido-3-thiazolidinyl)-3-methyl-, (2S,3S)-
L-Lysine, glycyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-α-glutamyl-L-α-aspartyl-L-valylglycylglycyl-6-aminohexanoyl-L-lysyl-L-lysyl-L-lysyl-L-lysyl-L-lysyl