4,6-Dichloro-1H-indazole
4,6-Dichloro-1H-indazole
CAS: 885519-58-4
Molecular Formula: C7H4Cl2N2
4,6-Dichloro-1H-indazole - Names and Identifiers
| Name | 4,6-Dichloro-1H-indazole |
| Synonyms | 4,6-dichloroindazole 4,6-Dichloro-1H-indazole 1H-Indazole, 4,6-dichloro- |
| CAS | 885519-58-4 |
| InChI | InChI=1S/C7H4Cl2N2/c8-4-1-6(9)5-3-10-11-7(5)2-4/h1-3H,(H,10,11) |
4,6-Dichloro-1H-indazole - Physico-chemical Properties
| Molecular Formula | C7H4Cl2N2 |
| Molar Mass | 187.03 |
| Storage Condition | Sealed in dry,Room Temperature |
4,6-Dichloro-1H-indazole - Introduction
4,6-Dichloro-1H-indazole is an organic compound with the chemical formula C7H3Cl2N. It is a yellow crystal with a special bitter taste. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: Yellow crystal
-Solubility: Soluble in organic solvents, such as ethanol, dimethylformamide, etc. Difficult to dissolve in water.
-Melting point: about 155-157°C
-Density: about 1.5g/cm³
Use:
4,6-Dichloro-1H-indazole has many applications in the chemical field, including the following:
-Intermediate: It can be used as an intermediate in organic synthesis and used to synthesize other compounds.
-Drug research: It has certain application potential in new drug research and medicinal chemistry, and can be used to synthesize biologically active compounds.
-Surface treatment agent: It can be used as a steel surface treatment agent and has certain applications in corrosion protection.
Preparation Method:
There are many methods for preparing 4,6-Dichloro-1H-indazole. The following is one of the commonly used synthetic routes:
1. First, the indazole was dissolved in acetic acid.
2. Add the aluminum trichloride of the refrigerant to reduce the temperature of the solution.
3. under low temperature conditions, add ferrous chloride at 1.1 points.
4. After completion of the reaction, the reaction mixture was diluted and filtered.
5. The solid product was washed with dilute hydrochloric acid and then air-dried to give 4,6-Dichloro-1H-indazole.
Safety Information:
- 4,6-Dichloro-1H-indazole is an organic compound and should be used with care and in accordance with appropriate laboratory practices.
-When handling or contacting the substance, wear appropriate protective equipment, such as gloves, protective glasses, etc.
-Avoid inhaling the gas or dust of the substance, and operate in a well-ventilated place.
-When storing, keep it in a sealed container, away from fire and oxidizing agents.
-In the event of an accident, flush the affected area immediately with plenty of water and seek medical help.
Please note that the above information is for reference only, and the specific preparation and use operations should be carried out according to the actual situation and laboratory conditions. Before conducting relevant experiments or applications, the relevant literature and safety technical specifications should be carefully read.
Nature:
-Appearance: Yellow crystal
-Solubility: Soluble in organic solvents, such as ethanol, dimethylformamide, etc. Difficult to dissolve in water.
-Melting point: about 155-157°C
-Density: about 1.5g/cm³
Use:
4,6-Dichloro-1H-indazole has many applications in the chemical field, including the following:
-Intermediate: It can be used as an intermediate in organic synthesis and used to synthesize other compounds.
-Drug research: It has certain application potential in new drug research and medicinal chemistry, and can be used to synthesize biologically active compounds.
-Surface treatment agent: It can be used as a steel surface treatment agent and has certain applications in corrosion protection.
Preparation Method:
There are many methods for preparing 4,6-Dichloro-1H-indazole. The following is one of the commonly used synthetic routes:
1. First, the indazole was dissolved in acetic acid.
2. Add the aluminum trichloride of the refrigerant to reduce the temperature of the solution.
3. under low temperature conditions, add ferrous chloride at 1.1 points.
4. After completion of the reaction, the reaction mixture was diluted and filtered.
5. The solid product was washed with dilute hydrochloric acid and then air-dried to give 4,6-Dichloro-1H-indazole.
Safety Information:
- 4,6-Dichloro-1H-indazole is an organic compound and should be used with care and in accordance with appropriate laboratory practices.
-When handling or contacting the substance, wear appropriate protective equipment, such as gloves, protective glasses, etc.
-Avoid inhaling the gas or dust of the substance, and operate in a well-ventilated place.
-When storing, keep it in a sealed container, away from fire and oxidizing agents.
-In the event of an accident, flush the affected area immediately with plenty of water and seek medical help.
Please note that the above information is for reference only, and the specific preparation and use operations should be carried out according to the actual situation and laboratory conditions. Before conducting relevant experiments or applications, the relevant literature and safety technical specifications should be carefully read.
Last Update：2024-04-10 22:41:03
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View History
4,6-Dichloro-1H-indazole
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