345-94-8 - Names and Identifiers
345-94-8 - Physico-chemical Properties
Molecular Formula | C9H8BrFO
|
Molar Mass | 231.06 |
Density | 1.488g/cm3 |
Melting Point | 35°C |
Boling Point | 260.8°C at 760 mmHg |
Flash Point | 111.5°C |
Solubility | Chloroform (Sparingly) |
Vapor Presure | 0.012mmHg at 25°C |
Appearance | Solid |
Color | White to Off-White |
Storage Condition | Amber Vial, Refrigerator |
Stability | Light Sensitive |
Refractive Index | 1.538 |
345-94-8 - Introduction
2-bromo-1-(4-fluorophenyl)propan-1-one is an organic compound with the chemical formula C9H9BrFO and a molecular weight of 225.07g/mol. The following is a detailed description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2-bromo-1-(4-fluorophenyl)propan-1-one as a colorless or pale yellow solid.
-Melting point: about 45-50 ℃.
-Boiling point: about 180-183 ℃.
-Solubility: 2-bromo-1-(4-fluorophenyl) is propan-1-one soluble in organic solvents such as ethanol and chloroform, and slightly soluble in water.
Use:
The -2-bromo-1-(4-fluorophenyl)propan-1-one can be used as an intermediate in organic synthesis. It is commonly used in the synthesis of drugs, fragrances and other organic compounds.
-In the pharmaceutical field, this compound may be used to synthesize the core structure of certain drugs.
-In the fragrance industry, it can be used as a raw material for the preparation of aromatherapy oil, perfume and other fragrance ingredients.
-It is also used as a reducing agent, oxidant and catalyst in organic synthesis reactions.
Preparation Method:
- 2-bromo-1-(4-fluorophenyl)propan-1-one can be prepared by reacting benzophenone with bromine and a fluorinating agent. A common preparation method involves reacting benzophenone with bromine and sulfur tetrafluoride, catalyzed by ferric chloride.
Safety Information:
- 2-bromo-1-(4-fluorophenyl)propan-1-one is a chemical and should be handled under appropriate laboratory conditions.
-This compound may be irritating and sensitive, and some may be carcinogenic. Therefore, the use should strictly abide by the relevant safety procedures, such as wearing appropriate protective equipment, maintaining good indoor ventilation.
-Use away from fire and heat sources, avoid contact with skin, eyes and mucous membranes.
-Observe local laws and regulations when handling and disposing of this compound and related waste.
Last Update:2024-04-09 20:48:19