1-(3-Chlorophenyl) cyclobutanomethylamine, chemical formula C10H15ClN, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: colorless or light yellow liquid
-Solubility: Soluble in organic solvents such as alcohols, ethers and chlorinated hydrocarbons
-Melting point:-5 ℃
-Boiling point: 213-216 ℃
-Density: Approximately 1.05 g/mL
-The compound can exist in two conformers with chirality.
Use:
- 1-(3-Chlorophenyl) cyclobutanemylamine has a central nervous system inhibitory effect similar to anesthetics and can be used as a drug intermediate.
-The compound can also be used in reduction reactions, carboxyl reduction reactions and hydrogenation reactions in organic synthesis.
Method:
The preparation method of -1-(3-chlorophenyl) cyclobutane methylamine usually reacts styrene with phosphorus oxychloride to generate 3-chlorostyrene, and then condenses with cyclobutane methanol under alkaline conditions to obtain the target product.
Safety Information:
-The compound should be handled in a well-ventilated place, avoiding inhalation or contact with skin and eyes.
-Mild irritation, may cause irritation to the eyes, skin and respiratory system, so need to pay attention to protective measures, such as wearing gloves and protective glasses.
-Store and handle the compound properly and follow the relevant safety procedures. In case of accident or discomfort, seek medical help immediately.