Molecular Formula | C31H52O3 |
Molar Mass | 472.75 |
Density | 0.96 g/mL at 20 °C(lit.) |
Melting Point | -27.5° |
Boling Point | bp0.01 184°; bp0.025 194°; bp0.3 224° |
Flash Point | 9℃ |
Storage Condition | 2-8℃ |
Refractive Index | 0 |
UN IDs | UN 1648 3 / PGII |
Chen Xuebing , Jiang Yiming , Korean army ,CHENXuebing,JIANGYiming,HANJun
Abstract:
Natural VE acetate was synthesized by esterification of natural VE with acetic anhydride. With the conversion rate as the index, through single factor experiments and orthogonal experiments, the optimum synthesis conditions were obtained as follows: reaction time 60 min, reaction temperature 110 ℃, the amount of acetic anhydride 45%, the amount of catalyst 4.0%. Under the optimum conditions, the conversion rate of VE acetate reached 99 4%.Key words:
Natural Vitamin E acetic anhydride Natural Vitamin E acetate synthesis
DOI:
CNKI:SUN:ZYZZ.0.2010-05-019
cited:
year:
2010
Author:
lo Chaji , Liu Aiqin , Yang Jincheng Xu Xinde , confluence Dragon
Abstract:
in order to improve the spray drying effect of synthetic vitamin E acetate dry powder and optimize the spray drying process, the inlet air temperature, inlet frequency, the influence of atomizer frequency and feed frequency on the spray drying effect of synthetic vitamin E powder, and the orthogonal test was used to optimize the spray drying conditions, the influence of atomizer frequency and feed frequency on product yield and product quality. The results show that when the inlet air temperature is 180 ℃, the inlet air frequency is 60Hz, the atomizer frequency is 40Hz, and the feed frequency is 40Hz, the product yield is the highest, up to 96.5%, the water content of the prepared vitamin E acetate dry powder was 3.5%, and the particle size was mainly distributed between 40-80 mesh.
Key words:
spray drying Process synthetic vitamin E acetate microcapsule
DOI:
10.3969/j.issn.1006-2513.2015.03.013
cited:
year:
2015
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.115 ml | 10.576 ml | 21.153 ml |
5 mM | 0.423 ml | 2.115 ml | 4.231 ml |
10 mM | 0.212 ml | 1.058 ml | 2.115 ml |
5 mM | 0.042 ml | 0.212 ml | 0.423 ml |
Abstract:
regulation of vitamin E acetate (VE-A) conversion in the intestine is important for the design of functional foods and beverages in the food industry. Previous studies mainly focused on the establishment of complex simulated digestive environment and the establishment of standard methods, but did not consider the crowding of macromolecules in the real human body. In addition, a common preparation method for VE-A emulsion is a micro-jet homogenization method or a self-emulsification method, and no ultrasonic method is used. Most of the studies investigated the effects of glyceryl trioctanoate (MCT) and glyceryl trioleate (LCT) on emulsion digestion, but not tributyrin (SCT). In this study, various concentrations of polyethylene glycol 2000(PEG2000) and polysucrose 400(Fico11400) were used as macromolecular crowding agents, and three kinds of chain length triglycerides were used as the oil phase mixed with VE-A, the emulsion was prepared by high-speed shear-assisted ultrasonic emulsification, and its effect on the hydrolysis efficiency of VE-A emulsion catalyzed by porcine pancreatic lipase (PPL) was investigated. (1) ultrasonic preparation VE-A Emulsion Stability study using high-speed shear assisted ultrasonic method to prepare VE-A emulsion, oil phase using SCT,MCT and LCT three kinds of loading oil and VE-A mixed grease, and the stability of the emulsion at room temperature after 24 h, and the stability of the study at different ambient temperatures. The results obtained for three kinds of loading oil preparation of emulsion at room temperature after 24 h and after 30 to 90 deg C water bath, can show a certain stability, the average particle size of emulsion prepared by SCT minimum, the absolute value of ζ-potential is the largest, and its stability is the highest. (2) the influence of Fico11400 crowding medium on the kinetics of lipase esterification in VE-A emulsion and the digestion rate of VE-A emulsion in vitro by adding different concentrations of Fico11400 in the emulsion system, the average particle size of the emulsion, effect of PPL catalyzed hydrolysis of three loading oils to produce VE-A emulsion efficiency, emulsion bioavailability, and VE-A conversion. From DLS, it can be seen that the average particle size of the emulsion increases steadily with the increase of the concentration of Fico11400 in the system. From the results of ITC, it can be seen that at all concentrations of Fico11400, Pancreatic Lipase catalyzed hydrolysis of three kinds of loading oil to prepare VE-A emulsion efficiency is higher than that in dilute solution, the catalytic efficiency of pancreatic lipase in the preparation of MCT emulsion was up to 3.05 times. And put this system into the more complex simulation of the small intestine environment, the VE-A conversion rate is also improved. Bioaccessibility:.LCT>MCT & asymp;SCT,VE-A conversion: SCT>LCT>MCT. (3) the effect of PEG2000 crowding medium on the kinetics of lipase esterification in VE-A emulsion and the in vitro digestion rate of VE-A emulsion, the particle size distribution of the emulsion is shifted to the right, that is, the average particle size is steadily increasing. The results obtained by ITC are as good as those in Fico11400, that is, at all concentrations of PEG2000, the VE-A emulsion preparation efficiency of the three loading oils catalyzed by pancreatic lipase is improved compared with that in dilute solution, the catalytic efficiency of pancreatic lipase in the emulsion prepared by SCT was up to 4.94 times. Put the system into the small intestine simulation environment, the law of the biological accessibility and the VE-A conversion rate is consistent with that of Fico11400, that is, the biological accessibility rate: LCT>MCT & asymp;SCT,VE-A conversion: SCT>LCT>MCT. From the above results, it can be seen that the large molecule crowding effect is universal in the system of the VE-A emulsion loaded with the Lipase catalyzed hydrolysis of triglycerides. In the ITC experiment, the hydrolysis efficiency of pancreatic lipase in the presence of PEG2000 was the largest in the preparation of VE-A emulsion of medium chain triglyceride (MCT). In Fico11400, Pancreatic Lipase catalyzed hydrolysis of short chain triglycerides (SCT) to prepare VE-A emulsion was the largest. In the in vitro simulated digestion, the bioavailability and the VE-A conversion rate of the VE-A emulsion prepared by the three kinds of loading oils showed the same law in both PEG2000 and Fico11400, that is, the bioavailability rate: LCT>MCT & asymp;SCT, vitamin E conversion rate: SCT>LCT>MCT. These findings have important implications for developing the design of emulsion delivery nutrient systems in the food industry and testing their potential efficiency.
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Key words:
macromolecular crowding vitamin E acetate conversion rate In vitro simulated digestion ultrasonic emulsification method