2-(3-Bromophenyl)pyridine - Names and Identifiers
2-(3-Bromophenyl)pyridine - Physico-chemical Properties
Molecular Formula | C11H8BrN
|
Molar Mass | 234.09 |
Density | 1.426±0.06 g/cm3(Predicted) |
Boling Point | 311.9±17.0 °C(Predicted) |
Flash Point | 142.427°C |
Vapor Presure | 0.001mmHg at 25°C |
Appearance | clear liquid |
Color | White to Yellow to Green |
pKa | 4.04±0.12(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | gt. 1.6480 to 1.6520 |
2-(3-Bromophenyl)pyridine - Introduction
2-(3-Bromophenyl)pyridine is an organic compound with the chemical formula C11H8BrN. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 2-(3-Bromophenyl)pyridine is a solid, usually light yellow crystals or powder.
-Solubility: It has good solubility in common organic solvents, such as ethanol, dichloromethane, etc.
-Melting point: Its melting point is about 75-80 degrees Celsius.
Use:
2-(3-Bromophenyl)pyridine, as an organic synthesis intermediate, has a wide range of applications.
-It can be used as a compound synthesis in the field of medicine, such as the synthesis of anticancer drugs.
-It can also be used as an important intermediate in the preparation of pesticides and insecticides.
Preparation Method:
The synthesis of 2-(3-Bromophenyl)pyridine can be carried out by the following reaction steps:
1. In a reaction solvent, 3-bromophenane and pyridine are reacted and heated to reflux.
2. As the reaction proceeds, the product will gradually form.
3. After the reaction, the product is purified by crystallization or other suitable methods.
Safety Information:
The following safety precautions are required when handling 2-(3-Bromophenyl)pyridine:
-It is an organic solvent, which is irritating to eyes, skin and respiratory system. Please avoid direct contact.
-Adequate ventilation and appropriate protective equipment such as goggles, gloves and respiratory protection are required during operation.
-When storing and handling, please keep away from fire and high temperature, and avoid contact with incompatible substances such as oxidants.
In general, 2-(3-Bromophenyl)pyridine is a compound commonly used in organic synthesis. It has a wide range of applications in the fields of medicine and pesticides, but safety measures should be paid attention to during operation. When used in industry and laboratories, strict compliance with safe operating procedures is required.
Last Update:2024-04-09 19:05:49