16-alpha-hydroxyprednisole-16,17-acetonide
Desonide
CAS: 638-94-8
Molecular Formula: C24H32O6
16-alpha-hydroxyprednisole-16,17-acetonide - Names and Identifiers
| Name | Desonide |
| Synonyms | d-2083 DESONIDE Desonide steroderm PREDNACINOLONE 16-alpha-hydroxyprednisole-16,17-acetonide 17-acetonide,16-alpha-hydroxy-prednisolone-1 1,4-PREGNADIEN-11-BETA, 16-ALPHA, 17,21-TETROL-3,20-DIONE 16,17-ACETONIDE (11b,16a)-11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-pregna-1,4-diene-3,20-dione |
| CAS | 638-94-8 |
| EINECS | 211-351-6 |
| InChI | InChI=1/C24H32O6/c1-21(2)29-19-10-16-15-6-5-13-9-14(26)7-8-22(13,3)20(15)17(27)11-23(16,4)24(19,30-21)18(28)12-25/h7-9,15-17,19-20,25,27H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,20+,22-,23-,24+/m0/s1 |
16-alpha-hydroxyprednisole-16,17-acetonide - Physico-chemical Properties
| Molecular Formula | C24H32O6 |
| Molar Mass | 416.51 |
| Density | 1.30±0.1 g/cm3(Predicted) |
| Melting Point | 272-274?C |
| Boling Point | 580.1±50.0 °C(Predicted) |
| Specific Rotation(α) | +119.0°- +124.0° (c=0.5, MeOH) |
| Flash Point | 196.9°C |
| Solubility | DMF (Slightly, Sonicated), DMSO (Sparingly), Methanol (Slightly, Heated) |
| Vapor Presure | 7.16E-16mmHg at 25°C |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | 12.87±0.10(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.598 |
| MDL | MFCD00866151 |
16-alpha-hydroxyprednisole-16,17-acetonide - Risk and Safety
| HS Code | 2937290000 |
| Toxicity | LD50 in rats (mg/kg): 93 s.c. (Phillips) |
16-alpha-hydroxyprednisole-16,17-acetonide - Reference Information
| Overview | desolide, is a kind of strong anti-inflammatory effect of corticosteroids. |
| uses | desoronide is a glucocorticoid drug, which has anti-inflammatory, anti-allergic, anti-itching and reducing exudation effects; can reduce and prevent tissue response to inflammation, can eliminate local non-infectious inflammation caused by Fever, redness and swelling, thereby reducing the performance of inflammation; With the prevention or inhibition of cellular immune response, the immunosuppressive effect of suppressing the primary immune response. |
| biological activity | Desonide is an inefficient topical corticosteroid hormone. |
| Target | Value |
Last Update：2024-04-09 20:52:54
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View History
16-alpha-hydroxyprednisole-16,17-acetonide
2-(2-BROMO-PHENYL)-2,3-DIHYDRO-BENZOFURAN-5-CARBOXYLIC ACID METHYL ESTER
BALSAM,CANADIAN
2H-Pyrrole-2-carboxylicacid,3,4-dihydro-5-(1-methylethyl)-(9CI)
3-(3-acetyl-4-(oxiran-2-ylMethoxy)phenyl)-1,1-diethylurea
Pyridinium, 3-(aminocarbonyl)-1,6-dimethyl-
5-Chloro-2-caynopyridine
91211-39-1
341964-96-3
1181761-93-2
2-(2-BROMO-PHENYL)-2,3-DIHYDRO-BENZOFURAN-5-CARBOXYLIC ACID METHYL ESTER
BALSAM,CANADIAN
2H-Pyrrole-2-carboxylicacid,3,4-dihydro-5-(1-methylethyl)-(9CI)
3-(3-acetyl-4-(oxiran-2-ylMethoxy)phenyl)-1,1-diethylurea
Pyridinium, 3-(aminocarbonyl)-1,6-dimethyl-
5-Chloro-2-caynopyridine
91211-39-1
341964-96-3
1181761-93-2