1351758-37-6
(2R)-2-hydroxy-3-(hydroxymethyl)-3-methyl-N-(3-oxo-4-phenylbutyl)butanamide
CAS: 1351758-37-6
Molecular Formula: C16H23NO4
1351758-37-6 - Names and Identifiers
1351758-37-6 - Physico-chemical Properties
| Molecular Formula | C16H23NO4 |
| Molar Mass | 293.36 |
| Density | 1.160±0.06 g/cm3(Predicted) |
| Boling Point | 559.5±50.0 °C(Predicted) |
| Solubility | 10 mM in DMSO |
| pKa | 13.00±0.20(Predicted) |
| Storage Condition | -20℃ |
| In vivo study | Oral administration of RR6 in Wistar rats (150-200 g) completely inhibited plasma vanin activity and caused alterations of plasma lipid concentrations upon fasting. RR6 at 3 mg/mL in rats caused a nearly complete inhibition of plasma vanin. |
1351758-37-6 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.409 ml | 17.044 ml | 34.088 ml |
| 5 mM | 0.682 ml | 3.409 ml | 6.818 ml |
| 10 mM | 0.341 ml | 1.704 ml | 3.409 ml |
| 5 mM | 0.068 ml | 0.341 ml | 0.682 ml |
Last Update：2024-01-02 23:10:35
1351758-37-6 - Reference Information
| biological activity | RR6 is a potent, selective, reversible, A competitive and orally active vanin inhibitor with an IC50 of 540 nM for recombinant vanin-1. RR6 also potently inhibited human, bovine and rat serum ubiquitin with IC50 values of 40 nM,41 nM and 87 nM, respectively. |
Last Update：2024-04-09 21:54:55
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CAS: 1351758-37-6
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View History
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