105426-14-0
Erdosteine
CAS: 84611-23-4;105426-14-0
Molecular Formula: C8H11NO4S2
105426-14-0 - Names and Identifiers
105426-14-0 - Physico-chemical Properties
| Molecular Formula | C8H11NO4S2 |
| Molar Mass | 249.31 |
| Density | 1.48±0.1 g/cm3(Predicted) |
| Melting Point | 156-160°C |
| Boling Point | 590.4±50.0 °C(Predicted) |
| Flash Point | 310.8°C |
| Solubility | Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly) |
| Vapor Presure | 1.82E-15mmHg at 25°C |
| Appearance | Solid |
| Color | White to Off-White |
| Maximum wavelength(λmax) | ['236nm(H2O)(lit.)'] |
| Merck | 14,3647 |
| pKa | 3.71(at 25℃) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.615 |
| Physical and Chemical Properties | Melting point 156-160°C |
| Use | Used as Expectorant Cough medicine for acute and chronic bronchitis, obstructive emphysema and other diseases |
105426-14-0 - Risk and Safety
| RTECS | AJ1476200 |
| Toxicity | LD50 in mice and rats (g/kg): >10 orally; >3.5 i.v. (Gonella) |
105426-14-0 - Nature
Open Data Verified Data
white crystals from ethanol, melting point 15 6-158 °c.
Last Update：2024-01-02 23:10:35
105426-14-0 - Preparation Method
Open Data Verified Data
after the reaction of ethyl chloroacetate and sodium sulfide, acidic hydrolysis was carried out in the presence of hydrochloric acid, followed by cyclization in the presence of acetyl chloride to give 3-thioglutaric anhydride. The high cysteine lactone hydrochloride dissolved in Tetrahydrofuran, after neutralized with sodium hydroxide aqueous solution, and 3 thioglutaric anhydride reaction, and sodium hydroxide aqueous solution to adjust the pH to 7~8, that is erdostat.
Last Update：2022-01-01 09:22:59
105426-14-0 - Use
Open Data Verified Data
erdostein was developed by the Italian company Refarmed and Edmond Pharma and was marketed in France under the trade names ediul and Vectrin in 1995 by the companies Pierce Fa-bre medicamide and Pharma 2000( Negma), in 1996, it was listed in Sweden under the trade name Mucofor by Vifor, under the trade name Esteclin by sakside, and in Mexico under the trade name Doflus by G1axo Well-come. Developed by Refarmed and Edmond Pharma, Italy, was first launched in France in 1995. Phlegm dissolving drugs can reduce sputum purulent and adhesion, and improve the inhibited respiratory function. Compared with similar products such as acetylcysteine, carboxy methyl, etc., the product has a good effect on acute and chronic bronchitis, and is more effective in improving some respiratory function parameters. For acute and chronic bronchitis, obstructive emphysema and other diseases Cough, Expectoration.
Last Update：2022-01-01 09:23:00
105426-14-0 - Safety
Open Data Verified Data
mouse, rat LD50(g/kg):>10 orally;>3.5 intravenously.
Last Update：2022-01-01 09:23:00
Supplier List
Featured ProductsSpot supply
Product Name: Erdosteine Visit Supplier Webpage Request for quotationCAS: 84611-23-4
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Multiple SpecificationsSpot supply
Product Name: RV 144 Visit Supplier Webpage Request for quotationCAS: 84611-23-4
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Product Name: Erdosteine Request for quotation
CAS: 84611-23-4
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
CAS: 84611-23-4
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Spot supply
Product Name: Erdosteine Visit Supplier Webpage Request for quotationCAS: 84611-23-4
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: Erdosteine Visit Supplier Webpage Request for quotationCAS: 84611-23-4
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Product Name: Erdosteine Request for quotation
CAS: 84611-23-4
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 84611-23-4
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Spot supply
Product Name: Erdosteine Visit Supplier Webpage Request for quotationCAS: 84611-23-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Featured ProductsSpot supply
Product Name: Erdosteine Visit Supplier Webpage Request for quotationCAS: 84611-23-4
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Multiple SpecificationsSpot supply
Product Name: RV 144 Visit Supplier Webpage Request for quotationCAS: 84611-23-4
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Product Name: Erdosteine Request for quotation
CAS: 84611-23-4
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
CAS: 84611-23-4
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Spot supply
Product Name: Erdosteine Visit Supplier Webpage Request for quotationCAS: 84611-23-4
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: Erdosteine Visit Supplier Webpage Request for quotationCAS: 84611-23-4
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Product Name: Erdosteine Request for quotation
CAS: 84611-23-4
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 84611-23-4
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Spot supply
Product Name: Erdosteine Visit Supplier Webpage Request for quotationCAS: 84611-23-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
105426-14-0
双频呐醇硼酸酯甲烷
N-(5-Amino-2-fluorophenyl)-2-(2,4-dichlorophenoxy)acetamide
Sulfomethyl-phenolic resin (SMP)
氢氧化铜(II)
5'-O-[bis(4-methoxyphenyl)phenylmethyl]-P-(4-chlorophenyl)thymidylyl-(3'->5')-2'-deoxy-N-(2-methyl-1-oxopropyl)guanosine 3'-benzoate
2-Cyclohexen-1-one, 3-methyl-5-phenyl-, oxime
1H-Cyclopent[c]isoxazole-1-ethanol,-alpha--ethylhexahydro-,[1(R*),3a-alpha-,6a-alpha-]-(9CI)
4-{[(5-methylhexan-2-yl)amino]methyl}benzene-1-sulfonamide
2,3-DIMETHYL-1-PENTENE
双频呐醇硼酸酯甲烷
N-(5-Amino-2-fluorophenyl)-2-(2,4-dichlorophenoxy)acetamide
Sulfomethyl-phenolic resin (SMP)
氢氧化铜(II)
5'-O-[bis(4-methoxyphenyl)phenylmethyl]-P-(4-chlorophenyl)thymidylyl-(3'->5')-2'-deoxy-N-(2-methyl-1-oxopropyl)guanosine 3'-benzoate
2-Cyclohexen-1-one, 3-methyl-5-phenyl-, oxime
1H-Cyclopent[c]isoxazole-1-ethanol,-alpha--ethylhexahydro-,[1(R*),3a-alpha-,6a-alpha-]-(9CI)
4-{[(5-methylhexan-2-yl)amino]methyl}benzene-1-sulfonamide
2,3-DIMETHYL-1-PENTENE