中文名 | PGS-IN-1 |
英文名 | PGS-IN-1 |
别名 | 化合物PGS-IN-1 |
英文别名 | PGS-IN-1 102271-49-8 α-(3,5-di-tert-butyl-4-hydroxybenzylidene)-γ-butyrolactone 2(3H)-Furanone, 3-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]dihydro-, (E)- 2(3H)-Furanone, 3-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]dihydro-, (E)- (9CI) |
CAS | 102271-49-8 |
化学式 | C19H26O3 |
分子量 | 302.41 |
密度 | 1.096±0.06 g/cm3(Predicted) |
沸点 | 429.1±45.0 °C(Predicted) |
酸度系数 | 11.51±0.50(Predicted) |
存储条件 | 2-8°C,避光,干燥,密封 |
体外研究 | The synthesized α-benzulidene-γ-butyrolactones are pure isomers (either cis or trans ). PGS-IN-1 is the trans isomer. PGS-IN-1 exhibits potent antiinflammatrory and PGS inhibitory activity (IC 50 =0.28 μM). PGS-IN-1 also shows potent inhibitory activity against 5-lipoxygenase (IC 50 =1.05 μM). |
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