Molecular Formula | C19H26O3 |
Molar Mass | 302.41 |
Density | 1.096±0.06 g/cm3(Predicted) |
Boling Point | 429.1±45.0 °C(Predicted) |
pKa | 11.51±0.50(Predicted) |
Storage Condition | 2-8°C,避光,干燥,密封 |
In vitro study | The synthesized α-benzulidene-γ-butyrolactones are pure isomers (either cis or trans ). PGS-IN-1 is the trans isomer. PGS-IN-1 exhibits potent antiinflammatrory and PGS inhibitory activity (IC 50 =0.28 μM). PGS-IN-1 also shows potent inhibitory activity against 5-lipoxygenase (IC 50 =1.05 μM). |