中文名 | 蛇根平定 |
英文名 | Deserpidine |
别名 | 地舍平 蛇根平定 去甲氧利血平 利血平杂质3 地舍平溶液, 100PPM 地舍平DESERPIDINE 17-甲氧基-18-[(3,4,5-三甲氧基苯甲酰)氧]育亨烷-16-甲酸甲酯 |
英文别名 | Harmonyl Canescine Raunormine DESERPIDINE Recanescine Reserpidine Deserpidine Deserpidic Acid Methyl Ester 3,4,5-Trimethoxybenzoate methyl 17-methoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylate 17a-Methoxy-18b-[(3,4,5-trimethoxybenzoyl)oxy]-3b,20a-yohimban-16b-carboxylic Acid Methyl Ester (3b,16b,17a,18b,20a)-17-Methoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-3,20-yohimban-16-carboxylic Acid Methyl Ester Methyl (3beta,16beta,17alpha,18beta,20alpha)-17-methoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylate methyl (3beta,16beta,17alpha,18beta,20alpha)-17-methoxy-18-{[(3,4,5-trimethoxyphenyl)carbonyl]oxy}yohimban-16-carboxylate 17.alpha.-Methoxy-18.beta.-[(3,4,5-trimethoxybenzoyl)oxy]-3.beta.,20.alpha.-yohimban-16.beta.-carboxylic acid methyl ester |
CAS | 131-01-1 |
EINECS | 205-004-8 |
化学式 | C32H38N2O8 |
分子量 | 578.65 |
InChI | InChI=1/C32H38N2O8/c1-37-24-12-17(13-25(38-2)29(24)39-3)31(35)42-26-14-18-16-34-11-10-20-19-8-6-7-9-22(19)33-28(20)23(34)15-21(18)27(30(26)40-4)32(36)41-5/h6-9,12-13,18,21,23,26-27,30,33H,10-11,14-16H2,1-5H3/t18-,21+,23-,26-,27+,30+/m1/s1 |
密度 | 1.2277 (rough estimate) |
熔点 | 228-232°; mp 230-232°; mp 138° and 226-232° with resolidification at 175° |
沸点 | 638.28°C (rough estimate) |
比旋光度 | D20 -163° (c = 0.5 in pyridine) |
闪点 | 362.7°C |
蒸汽压 | 3.87E-18mmHg at 25°C |
溶解度 | 氯仿 (微溶) 、甲醇 (微溶) |
折射率 | 1.6260 (estimate) |
酸度系数 | 6.68 in 40% methanol |
存储条件 | -20°C Freezer |
外观 | 固体 |
颜色 | White to Off-White |
体外研究 | Deserpidine is an effective ganglionic blocking agent, which differs from Reserpine only by the absence of a methoxy group at C-11. Deserpidine has been used in the treatment of hypertension and psychosis. In addition, Deserpidine appears to act as a controller of other cardiac disorders. |
上游原料 | 甲醇 |