t-Boc-N-Amido-PEG2-Azide - Names and Identifiers
t-Boc-N-Amido-PEG2-Azide - Physico-chemical Properties
Molecular Formula | C11H22N4O4
|
Molar Mass | 274.32 |
Storage Condition | Room Temprature |
t-Boc-N-Amido-PEG2-Azide - Upstream Downstream Industry
t-Boc-N-Amido-PEG2-Azide - Introduction
t-Boc-N-Amido-PEG2-Azide(t-Boc-N-Amido-PEG2-Azide) is a chemical substance that has the following properties:
1. Appearance: the common form is white to light yellow solid powder.
2. Solubility: t-Boc-N-Amido-PEG2-Azide has good solubility in some organic solvents (such as dimethyl sulfoxide, dimethyl formamide) and water.
t-Boc-N-Amido-PEG2-Azide are mainly used in the fields of biochemistry and medicinal chemistry. Common applications include:
1. Construction of PEG modifier: t-Boc-N-Amido-PEG2-Azide can be used as a modifier for coupling reaction with other compounds to construct polyethylene glycol (PEG) modifier.
2. Drug delivery: By combining drug molecules with t-Boc-N-Amido-PEG2-Azide, a drug delivery system with high water solubility and biocompatibility can be prepared, which helps to improve drug efficacy and reduce side effects.
The method of preparing t-Boc-N-Amido-PEG2-Azide is generally as follows:
1. First, N-azidoethyl-(triethoxysilyl)-aminoethanol is reacted with BIS (triethoxysilyl)-hydroquinone, A compound called N-azidoethyl-(triethoxysilyl)-hydroquinone Propyne (Boc-NH-PEG2-Azide) is obtained.
2. Then, the Boc-NH-PEG2-Azide is reacted with tert-butyl alcohol and triphenylphosphine to generate t-Boc-N-Amido-PEG2-Azide.
With regard to safety information, t-Boc-N-Amido-PEG2-Azide are chemicals that are potentially dangerous. During use, please strictly follow the safety operation procedures. In case of contact with skin or eyes, rinse immediately with plenty of water. At the same time, should avoid inhalation of its dust or gas. To ensure safety, please read the relevant safety data sheets and operating instructions carefully before operation, and use personal protective equipment, such as laboratory gloves and goggles.
Last Update:2024-04-09 21:11:58