kbt-1585
Lenampicillin Hydrochloride
CAS: 80734-02-7
Molecular Formula: C21H23N3O7S
kbt-1585 - Names and Identifiers
kbt-1585 - Physico-chemical Properties
| Molecular Formula | C21H23N3O7S |
| Molar Mass | 461.49 |
| Melting Point | 145° (dec) |
| Storage Condition | 2-8℃ |
| In vivo study | Lenampicillin hydrochloride (KBT-1585)(oral adminstration; 0-1000 mg/kg) does not lead to death in dogs, and maximum dose of in this acute toxicity study is recorded because of causing emesis.Lenampicillin hydrochloride (LAPC) are identified for it main metabolites in rat and dogs. The main metabolite in peripheral plasma is 2,3-butanediol in rats and dog, On the other hand, high levels of acetoin is found in portal plasma for early period after dosing of LAPC. These results shows that the biotransformation of promoiety in LAPC to acetoin carried out mainly in intestinal tissues, but acetoin is converted to 2,3-butanediol in liver. |
kbt-1585 - Risk and Safety
| Toxicity | LD50 in male, female rats, male, female mice (mg/kg): approx 10000, approx 10000, 8294, 8492 orally; 4362, 4471, 3576, 4284 s.c.; 876, 838, 711, 775 i.v.; in dogs (mg/kg): >300 orally (Ogino) |
kbt-1585 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.008 ml | 10.041 ml | 20.082 ml |
| 5 mM | 0.402 ml | 2.008 ml | 4.016 ml |
| 10 mM | 0.201 ml | 1.004 ml | 2.008 ml |
| 5 mM | 0.04 ml | 0.201 ml | 0.402 ml |
Last Update：2024-01-02 23:10:35
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Product Name: KBT 1585 hydrochloride Visit Supplier Webpage Request for quotationCAS: 80734-02-7
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Mobile: 609-228-6898
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