204384-67-8
Fmoc-D-phenylglycine(4-OtBu)
CAS: 204384-67-8
Molecular Formula: C27H27NO5
204384-67-8 - Names and Identifiers
204384-67-8 - Physico-chemical Properties
| Molecular Formula | C27H27NO5 |
| Molar Mass | 445.51 |
204384-67-8 - Introduction
Fmoc-D-phenylglycine(4-OtBu) is an amino acid derivative with the following properties:
1. Chemical properties: it is a white solid, insoluble in water, soluble in organic solvents such as methanol, dichloromethane. It is a D-type amino acid with chirality and high optical purity.
2. Use: Fmoc-D-phenylglycine(4-OtBu) is commonly used in peptide synthesis as a protecting group, used to prevent the reaction of amino acids. It can also be used in the synthesis of drugs, peptides and other organic compounds. In addition, it is also used in research to study the properties and biological activity of amino acids.
3. Preparation method: Fmoc-D-phenylglycine(4-OtBu) preparation method is more complex, usually need to be synthesized by multi-step reaction. Specifically, 4-tert-butoxyphenylglycine is first reacted with D-phenylalanine Ester, and then the protective group Fmoc is introduced, finally, the protecting group can be removed under appropriate conditions to obtain Fmoc-D-phenylglycine(4-OtBu).
Safety information: Fmoc-D-phenylglycine(4-OtBu) is generally relatively safe under normal conditions of use. However, during handling and synthesis, appropriate laboratory safety practices should be followed and necessary personal protective equipment should be used. At the same time, avoid contact with strong oxidants and strong acids to avoid adverse reactions.
1. Chemical properties: it is a white solid, insoluble in water, soluble in organic solvents such as methanol, dichloromethane. It is a D-type amino acid with chirality and high optical purity.
2. Use: Fmoc-D-phenylglycine(4-OtBu) is commonly used in peptide synthesis as a protecting group, used to prevent the reaction of amino acids. It can also be used in the synthesis of drugs, peptides and other organic compounds. In addition, it is also used in research to study the properties and biological activity of amino acids.
3. Preparation method: Fmoc-D-phenylglycine(4-OtBu) preparation method is more complex, usually need to be synthesized by multi-step reaction. Specifically, 4-tert-butoxyphenylglycine is first reacted with D-phenylalanine Ester, and then the protective group Fmoc is introduced, finally, the protecting group can be removed under appropriate conditions to obtain Fmoc-D-phenylglycine(4-OtBu).
Safety information: Fmoc-D-phenylglycine(4-OtBu) is generally relatively safe under normal conditions of use. However, during handling and synthesis, appropriate laboratory safety practices should be followed and necessary personal protective equipment should be used. At the same time, avoid contact with strong oxidants and strong acids to avoid adverse reactions.
Last Update：2024-04-09 21:11:58
