| Name | brofluthrinate |
| Synonyms | brofluthrinate flubrocythrinate (R,S)-αcyano-3-(4'-bromophenoxybenzyl)-(R,S)-2(4-difluoromethoxyphenyl)-3-methylbutyrate |
| Molecular Formula | C20H22BrF2NO4 |
| Physical and Chemical Properties | Chemical properties light yellow to dark brown liquid. Soluble in alcohol, ether, benzene, acetone and other organic solvents, insoluble in water. It is stable in neutral and slightly acidic media, and alkaline media is easy to hydrolyze. The light is relatively stable. |
| Use | Application of novel pyrethroid insecticides, acaricides, with high efficiency, broad-spectrum, long residual effect, the use of safe features. Mainly used for cereals, cotton, vegetables, citrus, tea and other crops, the control of a variety of pests, mites, including serious harm of cotton bollworm, diamondback moth, resistant pests, mites also have excellent effect. Because of its low toxicity to bees and high efficiency against the mites of bees, it is an ideal agent for apiculture. It is used for spraying 1000-1500 times of 5% emulsifiable concentrate for crops. For efficient, broad-spectrum insecticide, acaricide, a variety of pests, mites have a good effect |
Preparation of 4-difluoromethoxyphenyl-3'-methylbutyryl chloride 4-chloro-3'-methylbutyric acid in the presence of an acid-base catalyst to generate 4-hydroxy-3'-methylbutyric acid, and then difluoromethylation with difluorochloromethane to generate 4-difluoromethoxyphenyl-3'-methylbutyric acid, and then treated with PCl3 or SOCl2, 4-difluoromethoxyphenyl -3 '-methylbutyyl chloride is generated.
The preparation of α-cyano-3-(4 '-bromophenoxy) benzyl alcohol is prepared by the interaction of m-phenoxybenzaldehyde with bromine and sodium cyanide.
Synthesis of Bromofluthrin From the above-synthesized 4-difluoromethoxy -3 'methylbutyyl chloride and α-cyano-3-(4'-bromophenoxy) benzyl alcohol, Bromofluthrin was synthesized.