Molecular Formula | C15H21N3O2S3 |
Molar Mass | 371.54 |
Density | 1.35 |
Melting Point | 148-149° |
Boling Point | 599.8±60.0 °C(Predicted) |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Appearance | Solid |
Color | Off-White to Pale Yellow |
pKa | 13.71±0.20(Predicted) |
Storage Condition | 2-8°C(protect from light) |
In vitro study | Arotinolol shows its selectivity of β-adrenergic receptors, the result of Arotinolol for β1 and β2 adrenoceptors in 125 I-ICYP binding to rat cerebral cortical membranes with pK i value of 9.74 and 9.26 respectively. The selectively of β1 and β2 is equal. Arotinolol shows its potency for inhibiting the binding of the same radioligand to 5HT1B-serotonergic receptor site, Arotinolol displaces 125 I-ICYP binding to 5HT1B-receptors with the pK i values of 7.97 and 8.16 resepectively for β1 and β2 adrenergic receptors. |