N3-dU
2'-azido-2'-deoxyuridine
CAS: 26929-65-7
Molecular Formula: C9H11N5O5
N3-dU - Names and Identifiers
| Name | 2'-azido-2'-deoxyuridine |
| Synonyms | N3-dU 2'-Az-dU 2'-N3-2'-dU 2'-AZIDO-2'-DU 2''-AZIDO-D-URIDINE 2'-azido-2'-deoxyuridine 2'-AZIDO-2'-DEOXYURIDINE Uridine,2'-azido-2'-deoxy- 2'-Azido-2'-deoxy-D-uridine 1-(2-azido-2-deoxypentofuranosyl)pyrimidine-2,4(1H,3H)-dione |
| CAS | 26929-65-7 |
| EINECS | 248-113-6 |
| InChI | InChI=1/C9H11N5O5/c10-13-12-6-7(17)4(3-15)19-8(6)14-2-1-5(16)11-9(14)18/h1-2,4,6-8,15,17H,3H2,(H,11,16,18) |
N3-dU - Physico-chemical Properties
| Molecular Formula | C9H11N5O5 |
| Molar Mass | 269.22 |
| Melting Point | 149-153°C |
| Appearance | powder to crystal |
| Color | White to Almost white |
| Maximum wavelength(λmax) | ['260nm(lit.)'] |
| Storage Condition | 2-8°C |
| In vitro study | 2'-Azido-2'-deoxyuridine (N3dUrd) has IC 50 s of >350 μM for ribonucleotide reductase activity in chinese hamster ovary (CHO) and 3T6 cell. |
N3-dU - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S24/25 - Avoid contact with skin and eyes. S22 - Do not breathe dust. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 8-10-21 |
| HS Code | 29349990 |
N3-dU - Reference Information
| Biological activity | 2 '-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase (ribonucleotide reductase) inhibitor. 2 '-Azido-2'-deoxyuridine has anticancer activity. |
Last Update：2024-04-09 15:16:45
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