LT-E501
3-(benzothiazol-2-yl)-7-(diethylamino)-2-benzopyrone
CAS: 38215-36-0
Molecular Formula: C20H18N2O2S
LT-E501 - Names and Identifiers
| Name | 3-(benzothiazol-2-yl)-7-(diethylamino)-2-benzopyrone |
| Synonyms | LT-E501 Coumarin 6 3-(2-Benzothiazolyl)-7-(diethylamino)coumarin 3-(benzothiazol-2-yl)-7-(diethylamino)-2-benzopyrone 3-(1,3-Benzothiazol-2-yl)-7-(diethylamino)-2H-chromen-2-one 2H-1-Benzopyran-2-one, 3-(2-benzothiazolyl)-7-(diethylamino)- |
| CAS | 38215-36-0 |
| EINECS | 253-830-2 |
| InChI | InChI=1/C20H18N2O2S/c1-3-22(4-2)14-10-9-13-11-15(20(23)24-17(13)12-14)19-21-16-7-5-6-8-18(16)25-19/h5-12H,3-4H2,1-2H3 |
LT-E501 - Physico-chemical Properties
| Molecular Formula | C20H18N2O2S |
| Molar Mass | 350.43 |
| Density | 1.311g/cm3 |
| Melting Point | 205-208℃ |
| Boling Point | 570.1°C at 760 mmHg |
| Flash Point | 298.6°C |
| Water Solubility | NEGLIGIBLE |
| Solubility | NEGLIGIBLE |
| Vapor Presure | 5.19E-13mmHg at 25°C |
| Appearance | Form Powder, color Orange |
| pKa | 2.98±0.20(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Sensitive | It is easy to absorb moisture and is stable. Incompatible with strong oxidants. |
| Refractive Index | 1.69 |
| MDL | MFCD00041869 |
| Physical and Chemical Properties | Bioactive Coumarin 6 is a fluorescent dye, which can be used as a fluorescent probe in particle drug delivery system to study the mechanism of in vivo tracking, cell uptake and transport of drug delivery system. |
| Use | Use laser dye. |
LT-E501 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 8 |
| HS Code | 29329990 |
LT-E501 - Upstream Downstream Industry
LT-E501 - Reference
| Reference Show more | 1. Liu, Xinyan, et al. "Combination of essential oil from Zanthoxylum bungeanum Maxim. and a microemulsion system: Permeation enhancement effect on drugs with different lipophilicity and its mechanism." Journal of Drug Delivery Science and Technology 55 (2020 2. [IF=10.435] Yang Meng et al."Development of triptolide-nanoemulsion gels for percutaneous administration: physicochemical, transport, pharmacokinetic and pharmacodynamic characteristics."J Nanobiotechnol. 2017 Dec;15(1):1-15 3. [IF=6.419] Xixi Li et al."Combination immunotherapy of chlorogenic acid liposomes modified with sialic acid and PD-1 blockers effectively enhances the anti-tumor immune response and therapeutic effects."Drug Deliv. 2021;28(1):1849-1860 4. [IF=6.183] Tiankuan Li et al."PD-L1-targeted microbubbles loaded with docetaxel produce a synergistic effect for the treatment of lung cancer under ultrasound irradiation."Biomater Sci-Uk. 2020 Mar;8(5):1418-1430 5. [IF=4.192] Haibo Pan et al."Assembly of Oil-Based Microcapsules Coated with Proanthocyanidins as a Novel Carrier for Hydrophobic Active Compounds."J Agr Food Chem. 2020;68(20):5715–5722 6. [IF=3.981] Xinyan Liu et al."Combination of essential oil from Zanthoxylum bungeanum Maxim. and a microemulsion system: Permeation enhancement effect on drugs with different lipophilicity and its mechanism."J Drug Deliv Sci Tec. 2020 Feb;55:101309 7. [IF=3.246] Yu Xuan et al."Preparation and Characterization of PLGA–PEG–PLGA Nanoparticles Containing Salidroside and Tamoxifen for Breast Cancer Therapy."Aaps Pharmscitech. 2020 Apr;21(3):1-11 8. [IF=6.321] Yujie Zheng et al."Microemulsion Delivery System Improves Cellular Uptake of Genipin and Its Protective Effect against Aβ1-42-Induced PC12 Cell Cytotoxicity."Pharmaceutics. 2022 Mar;14(3):617 9. [IF=5.268] Xuling Chen et al."A novel multifunctional nanoparticles formed by molecular recognition between AS1411 aptamer and redox-responsive paclitaxel-nucleoside analogue prodrug for combination treatment of β-lapachone and paclitaxel."Colloid Surface B. 2022 Ap |
LT-E501 - Introduction
Almost insoluble in water.
Last Update：2022-10-16 17:25:01
LT-E501 - Nature
| Solubility | DMF: soluble |
| BRN | 1085798 |
| EPA chemical information | 2H-1-Benzopyran-2-one, 3-(2-benzothiazolyl)-7-(diethylamino)- (38215-36-0) |
Last Update：2024-04-09 20:52:54
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Product Name: Coumarin 6 Visit Supplier Webpage Request for quotationCAS: 38215-36-0
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View History
LT-E501
Inderm
gallium trichloride
Ethlenethiourea
Nsc21897
38789-75-2
Amyloid Bri Protein (1-34)
89-83-8
4-氯丁烯
288617-75-4
Inderm
gallium trichloride
Ethlenethiourea
Nsc21897
38789-75-2
Amyloid Bri Protein (1-34)
89-83-8
4-氯丁烯
288617-75-4
Raw Materials for LT-E501
Ethanol
Sodium hydroxide
Dichloromethane
N,N-Dimethylformamide
Phosphorus oxychloride
Chloroform
Potassium hydroxide
1-Butanol
1,2-Dichlorobenzene
3-Methoxypropylamine
Sodium hydroxide
Dichloromethane
N,N-Dimethylformamide
Phosphorus oxychloride
Chloroform
Potassium hydroxide
1-Butanol
1,2-Dichlorobenzene
3-Methoxypropylamine