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FT011

FT011

CAS: 1001288-58-9

Molecular Formula: C20H17NO5

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FT011 - Names and Identifiers

Name FT011
Synonyms FT011
SHP-627
(E)-2-[[3-(3-Methoxy-4-propargyloxyphenyl)-1-oxo-2-propenyl]amino]benzoic Acid
Benzoic acid, 2-[[(2E)-3-[3-methoxy-4-(2-propyn-1-yloxy)phenyl]-1-oxo-2-propen-1-yl]amino]-
CAS 1001288-58-9

FT011 - Physico-chemical Properties

Molecular FormulaC20H17NO5
Molar Mass351.35
Density1.307±0.06 g/cm3(Predicted)
Boling Point618.9±55.0 °C(Predicted)
Solubility DMSO: ≥ 29 mg/mL
pKa3.45±0.36(Predicted)
Storage Condition-20℃
In vivo study FT011 (100 mg/kg b.i.d., p.o., for 4 weeks) improves the cardiac function and and myocardial remodeling in myocardial infarction rats. Animal Model: Seventy male Sprague Dawley (SD) rats (weighing 200-250 g) Dosage: 100 mg/kg Administration: B.I.D., p.o. on day 7 after surgery, for 4 weeks Result: Increased ejection fraction, fraction shortening and preload recruitable stroke work.

FT011 - Preparation solution concentration reference

 1mg5mg10mg
1 mM2.846 ml14.231 ml28.461 ml
5 mM0.569 ml2.846 ml5.692 ml
10 mM0.285 ml1.423 ml2.846 ml
5 mM0.057 ml0.285 ml0.569 ml
Last Update:2024-01-02 23:10:35

FT011 - Reference Information

bioactivity FT011 is an anti-fibrotic agent that reduces mRNA expression of collagen I and III and inhibits collagen synthesis.
in vivo study FT011 (100 mg/kg B.I. d., p.o., for 4 weeks) improvements the cardiac function and and myocardial reconstruction in myocardial infection rats. Animal Model: Seventy male Sprague Dawley (SD) rats (weighting 200-250g) Dosage: 100 mg/kg Administration: B.I.D., p.o. on day 7 after surgery, for 4 weeks Result: Increased ejection fraction, fraction shortening and preload recruitable stroke work.
Animal Model: Seventy male Sprague Dawley (SD) rats (weighing 200-250 g)
Dosage: 100 mg/kg
Administration: B.I.D., p.o. on day 7 after surgery, for 4 weeks
Result: Increased ejection fraction, fraction shortening and preload recruitable stroke work.
Last Update:2024-04-09 15:16:41
FT011
Supplier List
Shanghai Amole Biotechnology Co., Ltd.
Multiple SpecificationsSpot supply
Product Name: (E)-2-(3-(3-Methoxy-4-(prop-2-yn-1-yloxy)phenyl)acrylamido)benzoicacid Request for quotation
CAS: 1001288-58-9
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Shanghai Macklin Biochemical Co., Ltd
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Product Name: FT011  Visit Supplier Webpage Request for quotation
CAS: 1001288-58-9
Tel: +86-18821248368
Email: Int06@meryer.com
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MedChemExpress (MCE)
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Product Name: FT011 (Standard) Visit Supplier Webpage Request for quotation
CAS: 1001288-58-9
Tel: 609-228-6898
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     tech@medchemexpress.com
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SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: FT011 Visit Supplier Webpage Request for quotation
CAS: 1001288-58-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
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Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: FT011 Visit Supplier Webpage Request for quotation
CAS: 1001288-58-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Shanghai Amole Biotechnology Co., Ltd.
Multiple SpecificationsSpot supply
Product Name: (E)-2-(3-(3-Methoxy-4-(prop-2-yn-1-yloxy)phenyl)acrylamido)benzoicacid Request for quotation
CAS: 1001288-58-9
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: FT011  Visit Supplier Webpage Request for quotation
CAS: 1001288-58-9
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
MedChemExpress (MCE)
Multiple SpecificationsSpot supply
Product Name: FT011 (Standard) Visit Supplier Webpage Request for quotation
CAS: 1001288-58-9
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: FT011 Visit Supplier Webpage Request for quotation
CAS: 1001288-58-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: FT011 Visit Supplier Webpage Request for quotation
CAS: 1001288-58-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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