CS-1801
IKK epsilon-IN-1
CAS: 1292310-49-6
Molecular Formula: C26H27N5O3
CS-1801 - Names and Identifiers
CS-1801 - Physico-chemical Properties
| Molecular Formula | C26H27N5O3 |
| Molar Mass | 457.52 |
| Density | 1.32±0.1 g/cm3(Predicted) |
| Boling Point | 727.2±70.0 °C(Predicted) |
| Solubility | DMSO: 21.5 mg/mL |
| pKa | 5.25±0.40(Predicted) |
| Storage Condition | -20℃ |
| In vitro study | TBK1/IKKε-IN-2 (Cmpound #1) inhibits TBK1 biochemical function in Ulight kinase assay at 5 and 250 μM ATP concentration with IC 50 s of 0.6 and 2.6 nM, rsespectively. TBK1/IKKε-IN-2 inhibits IKKε biochemical function in Ulight kinase assay at 10 μM ATP with an IC 50 of 3.9 nM. The IC 50 of TBK1/IKKε-IN-2 in the Panc 02.13 proliferation assay is 5 μM. |
CS-1801 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.186 ml | 10.928 ml | 21.857 ml |
| 5 mM | 0.437 ml | 2.186 ml | 4.371 ml |
| 10 mM | 0.219 ml | 1.093 ml | 2.186 ml |
| 5 mM | 0.044 ml | 0.219 ml | 0.437 ml |
Last Update：2024-01-02 23:10:35
CS-1801 - Introduction
IKK epsilon-IN-1 is a chemical compound whose chemical properties are a white solid. It is an inhibitor of IKK epsilon (I κB kinase epsilon) and is used to inhibit the activity of the enzyme IKK Epsilon.
ikkε is an important signaling pathway protein kinase, which is involved in the regulation of immune system and apoptosis. IKKε-IN-1 can intervene and regulate these cellular processes by inhibiting the activity of ikkε. Therefore, IKKε-IN-1 is often used to study the biological function of the ikkε pathway, the signal transmission mechanism and the potential drug development target.
I can't provide specific information about the preparation of the IKK epsilon-IN-1, as it is a patent and trade secret. In general, it is synthesized by organic synthetic chemical methods.
As for the safety information about IKK epsilon-IN-1, due to the lack of specific research data, the safety and toxicity of the individual are not yet clear. Therefore, chemical procedures and laboratory safety guidelines should be strictly followed during research and application. In the process of use, should wear personal protective equipment, such as protective glasses, protective gloves, etc., to avoid direct contact with the skin and inhalation of dust particles. In addition, the IKK epsilon-IN-1 should be stored properly, away from high temperature, ignition and flammable substances. When obtaining and using the compound, it is best to purchase it from legal and compliant channels and follow relevant regulations.
ikkε is an important signaling pathway protein kinase, which is involved in the regulation of immune system and apoptosis. IKKε-IN-1 can intervene and regulate these cellular processes by inhibiting the activity of ikkε. Therefore, IKKε-IN-1 is often used to study the biological function of the ikkε pathway, the signal transmission mechanism and the potential drug development target.
I can't provide specific information about the preparation of the IKK epsilon-IN-1, as it is a patent and trade secret. In general, it is synthesized by organic synthetic chemical methods.
As for the safety information about IKK epsilon-IN-1, due to the lack of specific research data, the safety and toxicity of the individual are not yet clear. Therefore, chemical procedures and laboratory safety guidelines should be strictly followed during research and application. In the process of use, should wear personal protective equipment, such as protective glasses, protective gloves, etc., to avoid direct contact with the skin and inhalation of dust particles. In addition, the IKK epsilon-IN-1 should be stored properly, away from high temperature, ignition and flammable substances. When obtaining and using the compound, it is best to purchase it from legal and compliant channels and follow relevant regulations.
Last Update：2024-04-09 21:31:56
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Featured ProductsSpot supply
Product Name: IKK(epsilon)-IN-1, IKKE-IN-1 Visit Supplier Webpage Request for quotationCAS: 1292310-49-6
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: Ikkε-in-1 Request for quotationCAS: 1292310-49-6
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: TBK1/IKKε-IN-2 Visit Supplier Webpage Request for quotationCAS: 1292310-49-6
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: TBK1/IKKε-IN-2 Visit Supplier Webpage Request for quotationCAS: 1292310-49-6
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: IKK epsilon-IN-1 Visit Supplier Webpage Request for quotationCAS: 1292310-49-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
CS-1801
2-ETHYLACRYLIC ACID 98
PENTAFLUOROBENZYL CHLORIDE
Methyl carbonochloridate
C.I. Disperse Red 17 press cake
Ambroxol Impurity 81
NSC 269585
CYANOPHOS
2014-83-7
2-ETHYLACRYLIC ACID 98
PENTAFLUOROBENZYL CHLORIDE
Methyl carbonochloridate
C.I. Disperse Red 17 press cake
Ambroxol Impurity 81
NSC 269585
CYANOPHOS
2014-83-7