CS-1773
SH-4-54
CAS: 1456632-40-8
Molecular Formula: C29H27F5N2O5S
CS-1773 - Names and Identifiers
CS-1773 - Physico-chemical Properties
| Molecular Formula | C29H27F5N2O5S |
| Molar Mass | 610.59 |
| Density | 1.431±0.06 g/cm3(Predicted) |
| Boling Point | 717.2±70.0 °C(Predicted) |
| Solubility | 10 mM in DMSO |
| pKa | 4.29±0.10(Predicted) |
| Storage Condition | -20℃ |
| In vitro study | SH-4-54 exhibits unprecedented cytotoxicity in human glioblastoma brain tumor hepatocytes (BTSCs), but not in human embryonic astrocytes. In addition, SH-4-54 effectively inhibits STAT3 phosphorylation and its downstream transcriptional targets. |
| In vivo study | In BT73 orthotopic xenograft mice, SH-4-54 (10 mg/kg, I. P.) exhibited BBB permeability, effectively inhibited glial tumor growth, and inhibited pstat3. |
CS-1773 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.638 ml | 8.189 ml | 16.378 ml |
| 5 mM | 0.328 ml | 1.638 ml | 3.276 ml |
| 10 mM | 0.164 ml | 0.819 ml | 1.638 ml |
| 5 mM | 0.033 ml | 0.164 ml | 0.328 ml |
Last Update：2024-01-02 23:10:35
CS-1773 - Introduction
SH-4-54 is an organic compound with the chemical name (E)-2-({[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)) oxolan-2-yl]amino}(4-hydroxyphenyl)methyl) propanedinitril.
SH-4-54 is an anticancer drug with anti-tumor activity. It fights cancer cells by inhibiting cell proliferation and inducing apoptosis. SH-4-54 can be used as a drug candidate for targeted treatment of tumors.
The preparation method of SH-4-54 is mainly through the method of organic synthesis. A specific method comprises reacting appropriate starting materials under specific reaction conditions to give the target compound SH-4-54.
Regarding safety information, SH-4-54 is a laboratory-synthesized compound that is toxic and dangerous. Laboratory safety regulations must be observed during operation and use, and appropriate protective equipment must be worn to ensure safe operation. In addition, it should be stored in a dry, well-ventilated place, away from ignition and flammable substances.
SH-4-54 is an anticancer drug with anti-tumor activity. It fights cancer cells by inhibiting cell proliferation and inducing apoptosis. SH-4-54 can be used as a drug candidate for targeted treatment of tumors.
The preparation method of SH-4-54 is mainly through the method of organic synthesis. A specific method comprises reacting appropriate starting materials under specific reaction conditions to give the target compound SH-4-54.
Regarding safety information, SH-4-54 is a laboratory-synthesized compound that is toxic and dangerous. Laboratory safety regulations must be observed during operation and use, and appropriate protective equipment must be worn to ensure safe operation. In addition, it should be stored in a dry, well-ventilated place, away from ignition and flammable substances.
Last Update：2024-04-09 20:52:54
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