CHIDAMIDE
Chidamide
CAS: 743420-02-2
Molecular Formula: C22H19FN4O2
CHIDAMIDE - Names and Identifiers
CHIDAMIDE - Physico-chemical Properties
| Molecular Formula | C22H19FN4O2 |
| Molar Mass | 390.4102632 |
| Density | 1.336±0.06 g/cm3(Predicted) |
| Melting Point | >145°C (dec.) |
| Boling Point | 600.2±55.0 °C(Predicted) |
| Solubility | DMSO (Slightly), Methanol (Slightly, Sonicated) |
| Appearance | Solid |
| Color | Off-White to Pale Beige |
| pKa | 12.30±0.70(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
| Physical and Chemical Properties | Bioactive HDAC-IN-7 (Chidamide impurity) is an impurity of Chidamide. Chidamide is an effective, orally available HDAC class I HDAC1/2/3 and class IIb HDAC10 inhibitor. |
| Use | Role chidamide inhibits the cell cycle of lymphatic and hematological tumors and induces tumor cell apoptosis through the inhibition of specific HDAC subtypes and the resulting chromatin remodeling and gene transcription regulation (I. e. epigenetic regulation); Induce and enhance the tumor killing effect mediated by natural killer cells (NK) and antigen-specific cytotoxic T cells (CTL) and inhibit the inflammatory response of tumor pathological tissues, it can not only directly contribute to the therapeutic effect on circulating tumor cells and local lesions in T lymphoma, but also may be applied to induce and enhance the overall regulatory activity of anti-tumor cell immunity against other types of tumors. |
CHIDAMIDE - Upstream Downstream Industry
CHIDAMIDE - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.561 ml | 12.807 ml | 25.614 ml |
| 5 mM | 0.512 ml | 2.561 ml | 5.123 ml |
| 10 mM | 0.256 ml | 1.281 ml | 2.561 ml |
| 5 mM | 0.051 ml | 0.256 ml | 0.512 ml |
Last Update：2024-01-02 23:10:35
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Product Name: Chidamide impurity Visit Supplier Webpage Request for quotationCAS: 743420-02-2
Tel: 609-228-6898
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Mobile: 609-228-6898
Product Name: Chidamide Visit Supplier Webpage Request for quotation
CAS: 743420-02-2
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CAS: 743420-02-2
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Raw Materials for CHIDAMIDE