Azidoethanol
2-Azidoethanol
CAS: 1517-05-1
Molecular Formula: C2H5N3O
Azidoethanol - Names and Identifiers
| Name | 2-Azidoethanol |
| Synonyms | Ccris 4996 Azidoethanol 2-Azidoethanol 2-Azido-1-ethanol Ethanol, 2-azido- Azido-PEG1-alcohol 2-Hydroxyethyl azide |
| CAS | 1517-05-1 |
Azidoethanol - Physico-chemical Properties
| Molecular Formula | C2H5N3O |
| Molar Mass | 87.08 |
| Density | 1.1460 |
| Boling Point | 77℃ (24 Torr) |
| Storage Condition | Room Temprature |
| Refractive Index | 1.4264 (estimate) |
| Use | Uses 2-azidoethanol is an organic intermediate, which can be prepared by one-step reaction of 2-bromoethanol and sodium azide. There are reports that it can be used to prepare click cross-linked fluorescent polymers. |
Azidoethanol - Upstream Downstream Industry
| Downstream Products | Ethane, 1-azido-2-bromo- |
Azidoethanol - Reference
| Reference Show more | 1. [IF=11.556] Yuwei Li et al."pH-responsive DNA nanomicelles for chemo-gene synergetic therapy of anaplastic large cell lymphoma."Theranostics. 2020; 10(18): 8250–8263 |
Azidoethanol - Preparation
2-bromoethanol (12.5g,100.0mmol,1.0equiv.) is weighed into a 100mL round bottom flask, purified water (30mL) is added, stirred and dissolved, then sodium azide (7.8g,120.0mmol,1.2equiv.) is slowly added, the reaction is placed in a room temperature environment, and refluxed at 100 ℃ for 12 hours. The reaction solution was extracted with dichloromethane (25mL * 3), the organic phase was dried with anhydrous magnesium sulfate, the organic phase was removed by concentration under reduced pressure, and the next step was directly carried out after vacuum drying.
Last Update：2024-04-10 22:29:15
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