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979-92-0

5'-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE

CAS: 979-92-0

Molecular Formula: C14H20N6O5S

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  5. 979-92-0

979-92-0 - Names and Identifiers

Name 5'-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE
Synonyms Adenosylhomocysteine
Adenosyl-L-homocysteine
S-Adenosyl-L-Homocysteine (50 mg)
5'-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE
L-5'-S-(3-AMino-3-carboxypropyl)- 5'-thioadenosine
5-S'-[(S)-3-Amino-3-carboxypropyl]-5'-thioadenosine
5μ-Deoxy-S-adenosyl-L-homocysteine, AdoHcy, S-(5μ-Deoxyadenosine-5μ)-L-homocysteine
(2S)-2-amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methylsulfanyl]butanoic acid
S-(5′-Adenosyl)-L-homocysteine,5′-Deoxy-S-adenosyl-L-homocysteine, AdoHcy, S-(5′-Deoxyadenosine-5′)-L-homocysteine
CAS 979-92-0
EINECS 213-560-8
InChIKey ZJUKTBDSGOFHSH-WFMPWKQPSA-N

979-92-0 - Physico-chemical Properties

Molecular FormulaC14H20N6O5S
Molar Mass384.41
Density1.91±0.1 g/cm3(Predicted)
Melting Point209-211 °C
Boling Point787.5±70.0 °C(Predicted)
Solubility Soluble in hot water, slightly soluble in cold water, ethanol, very slightly soluble in ether
Appearancecrystalline
ColorOff-White to Brown
BRN99188
pKa2.22±0.10(Predicted)
Storage Condition-20°C
MDLMFCD00037388
Physical and Chemical PropertiesBioactive S-Adenosyl-L-homocysteine (SAH, S-Adenosylhomocysteine, AdoHcy, Formycinylhomocysteine) is an (Methyltransferase Like 3-14) inhibitor of METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 value of 0.9 μM.

979-92-0 - Risk and Safety

WGK Germany3
FLUKA BRAND F CODES8-10-23
HS Code2934990002

979-92-0 - Upstream Downstream Industry

Raw MaterialsAdenosine, 5'-S-[(3S)-3-amino-3-carboxypropyl]-2',3'-O-(1-methylethylidene)-5'-thio- (9CI)
DL-Homocysteine
FORMIMINOGLYCINE
NLUNILBRZXYZNX-KITWJDSFSA-N
5′-Chloro-5′-deoxy-2′,3′-O-isopropylideneadenosine
L-HOMOCYSTEINE
5'-CHLORO-5'-DEOXYADENOSINE
Adenosine
Adenosine triphosphate
Downstream Products5'-DEOXYADENOSINE

979-92-0 - Reference

Reference
Show more
1. [IF=2.752] Yuting Zhang et al."Metabolomic Analysis and Identification of Sperm Freezability-Related Metabolites in Boar Seminal Plasma."Animals-Basel. 2021 Jul;11(7):1939

979-92-0 - Introduction

5 '-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE(5'-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE) is a compound with important biological activity. It is a structural analog of S-adenosyl-L-homocysteine in which the 5 '-oxygen atom in the glycoside group has been removed. It is a white crystalline powder with good solubility in water.

5 '-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE plays a key regulatory role in cells. It is involved in a number of important biological processes, including DNA repair, gene expression, methylation and acetylation. In addition, it is also involved in antioxidant, anti-inflammatory and immune regulation and other physiological processes.

The preparation of 5 '-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE is generally carried out by a chemical synthesis method. It can be synthesized from the reaction of adenosine and L-homocysteine.

Regarding safety, the toxicity of 5 '-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE is low. However, due to its regulatory effect in cells, the application of large doses may cause some adverse reactions. In the process of use, it is necessary to carry out appropriate dosage and treatment according to the specific situation. In addition, during storage and handling, it is necessary to avoid contact with oxygen to avoid oxidative deactivation.
Last Update:2024-04-09 21:54:55
979-92-0
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Email: Int06@meryer.com
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Email: sales@chinaskyrun.com
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Product Name: 5'-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE Visit Supplier Webpage Request for quotation
CAS: 979-92-0
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View History
979-92-0
149682-77-9
SF110011
68511-50-2
117-02-2
50809-32-0
75472-93-4
15548-89-7
62036-49-1
4124-41-8
Raw Materials for 979-92-0
Adenosine, 5'-S-[(3S)-3-amino-3-carboxypropyl]-2',3'-O-(1-methylethylidene)-5'-thio- (9CI)
DL-Homocysteine
FORMIMINOGLYCINE
NLUNILBRZXYZNX-KITWJDSFSA-N
5′-Chloro-5′-deoxy-2′,3′-O-isopropylideneadenosine
Adenosine
Adenosine triphosphate
Downstream Products for 979-92-0
5'-DEOXYADENOSINE
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