896705-16-1
BMH-21
CAS: 896705-16-1
Molecular Formula: C21H20N4O2
896705-16-1 - Names and Identifiers
896705-16-1 - Physico-chemical Properties
| Molecular Formula | C21H20N4O2 |
| Molar Mass | 360.41 |
| Solubility | 10 mM in DMSO |
| Appearance | powder |
| Color | light yellow to dark yellow |
| Storage Condition | 2-8°C |
| In vitro study | BMH-21 causes proteasome-dependent destruction of RPA194, the large catalytic subunit protein of Pol I holocomplex. In U2OS cancer cell line, BMH-21 results in degradation of RPA194 and translocation of NCL with IC50 of 0.05 μM and 0.07 μM, respectively. By causing nucleolar stress, BMH-21 also shows potent inhibition on cell viability. |
| In vivo study | BMH-21 reduces tumor growth in mouse xenografts. |
896705-16-1 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
896705-16-1 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.775 ml | 13.873 ml | 27.746 ml |
| 5 mM | 0.555 ml | 2.775 ml | 5.549 ml |
| 10 mM | 0.277 ml | 1.387 ml | 2.775 ml |
| 5 mM | 0.055 ml | 0.277 ml | 0.555 ml |
Last Update：2024-01-02 23:10:35
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View History
896705-16-1
3-AMINO-4-(METHYLTHIO)BENZOTRIFLUORIDE
氨基三唑
2209090-47-9
952569-38-9
C.I.酸性黑107
90114-17-3
乙酸汞盐
Phenyl carbonochloridic acid
13244-57-0
3-AMINO-4-(METHYLTHIO)BENZOTRIFLUORIDE
氨基三唑
2209090-47-9
952569-38-9
C.I.酸性黑107
90114-17-3
乙酸汞盐
Phenyl carbonochloridic acid
13244-57-0