| Molecular Formula | C10H18Cl2N2 |
| Molar Mass | 237.17 |
| Density | 1.1961 (rough estimate) |
| Melting Point | 222-224°C(lit.) |
| Boling Point | 378.54°C (rough estimate) |
| Flash Point | 104.9°C |
| Water Solubility | SOLUBLE |
| Solubility | Soluble in water, insoluble in ethanol |
| Vapor Presure | 0.0121mmHg at 25°C |
| Appearance | White-like or gray powder |
| Color | off-white to gray |
| BRN | 5132096 |
| Storage Condition | room temp |
| Stability | Stable. Incompatible with strong oxidizing agents, strong bases. |
| Sensitive | Light Sensitive |
| Refractive Index | 1.6400 (estimate) |
| MDL | MFCD00012482 |
| Use | This product is for scientific research only and shall not be used for other purposes. |
| In vitro study | TMPD (N,N,N′,N′-tetramethyl-para-phenylene-diamine) is used in cell culture and microbiology to differentiate organisms that exhibit cytochrome c oxidase activity and to distinguish between Gram-negative and Gram-positive pathogenic and non-pathogenic bacteria. The concept of TMPD oxidation by microorganisms is widely used and is known as a successful colorimetric indicator for bacterial oxidases, as the radical cation TMPD+˙, formed by oxidation, shows a characteristic deep blue colour. The electrochemical recognition of the TMPD oxidation by bacterial oxidases can be applied to a variety of pathogens. |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R40 - Limited evidence of a carcinogenic effect |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S36/37 - Wear suitable protective clothing and gloves. S22 - Do not breathe dust. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | 2811 |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 8 |
| TSCA | Yes |
| HS Code | 29215190 |
| Hazard Class | 6.1(a) |
| Packing Group | II |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Overview | N,N,N',N'-tetramethyl-p-phenylenediamine dihydrochloride, short for TMPD, is an oxidase reagent, can be used to identify Neisseria gonorrhoeae. |
| Application | N,N,N',N'-tetramethyl-p-phenylenediamine dihydrochloride, can be used to identify Neisseria gonorrhoeae. The principle is that Neisseria gonorrhoeae has an oxidase, and the oxygen ions it produces can oxidize the oxidase reagent (N,N,N',N'-tetramethyl-p-phenylenediamine dihydrochloride) into a quinone compound, which causes a color reaction. |
| biological activity | TMPD dihydrozolide, a compound susceptible to oxidation, it is a redox-active substrate molecule for enzymatic conversion. TMPD dihydrochloride is also an electron donor and acts as a reducing co-substrate for heme peroxidase. TMPD dihydrochloride is also a substrate for complex IV. |