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637-01-4

N,N,N',N'-tetramethyl-p-phenylenediamine dihydrochloride

CAS: 637-01-4

Molecular Formula: C10H18Cl2N2

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637-01-4 - Names and Identifiers

Name N,N,N',N'-tetramethyl-p-phenylenediamine dihydrochloride
Synonyms N,N,N'
TetramethylPPhenylenediamineDihcl
Wurster's reagent dihydrochloride
TETRAMETHYL-P-PHENYLENEDIAMINE 2 HCL
N,N,N',N'-Tetramethylbenzol-1,4-diamindihydrochlorid
N,N,N',N'-TETRAMETHYL-P-*PHENYLENEDIAMIN E DIHYDROCH
N,N,N',N'-Tetramethyl-p-phenylenediammonium dichloride
NNN'N'-Tetramethyl-p-phenylene-diamine dihydrochloride
N,N,N',N'-Tetramethyl-P-phenylenediaminedihydrochloride
N,N,N',N'-tetramethyl-p-phenylenediamine dihydrochloride
N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride
N,N,N',N'-Tetramethylbenzene-1,4-diamine dihydrochloride
N,N,N',N'-TETRAMETHYL-1,4-BENZENEDIAMINE DIHYDROCHLORIDE
N,N,N',N'-TETRAMETHYL-1,4-BENZENEDIAMINE, DIHYDROCHLORIDE
N,N,N',N'-TETRAMETHYL-1,4-PHENYLENEDIAMINE DIHYDROCHLORIDE
1,4-Benzenediamine, N,N,N',N'-tetramethyl-, dihydrochloride
CAS 637-01-4
EINECS 211-274-8
InChI InChI=1/C10H16N2.2ClH/c1-11(2)9-5-7-10(8-6-9)12(3)4;;/h5-8H,1-4H3;2*1H

637-01-4 - Physico-chemical Properties

Molecular FormulaC10H18Cl2N2
Molar Mass237.17
Density1.1961 (rough estimate)
Melting Point222-224°C(lit.)
Boling Point378.54°C (rough estimate)
Flash Point104.9°C
Water SolubilitySOLUBLE
Solubility Soluble in water, insoluble in ethanol
Vapor Presure0.0121mmHg at 25°C
AppearanceWhite-like or gray powder
Coloroff-white to gray
BRN5132096
Storage Conditionroom temp
StabilityStable. Incompatible with strong oxidizing agents, strong bases.
SensitiveLight Sensitive
Refractive Index1.6400 (estimate)
MDLMFCD00012482
UseThis product is for scientific research only and shall not be used for other purposes.
In vitro study TMPD (N,N,N′,N′-tetramethyl-para-phenylene-diamine) is used in cell culture and microbiology to differentiate organisms that exhibit cytochrome c oxidase activity and to distinguish between Gram-negative and Gram-positive pathogenic and non-pathogenic bacteria. The concept of TMPD oxidation by microorganisms is widely used and is known as a successful colorimetric indicator for bacterial oxidases, as the radical cation TMPD+˙, formed by oxidation, shows a characteristic deep blue colour. The electrochemical recognition of the TMPD oxidation by bacterial oxidases can be applied to a variety of pathogens.

637-01-4 - Risk and Safety

Risk CodesR36/37/38 - Irritating to eyes, respiratory system and skin.
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R40 - Limited evidence of a carcinogenic effect
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S36/37 - Wear suitable protective clothing and gloves.
S22 - Do not breathe dust.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs2811
WGK Germany3
FLUKA BRAND F CODES8
TSCAYes
HS Code29215190
Hazard Class6.1(a)
Packing GroupII

637-01-4 - Introduction

Microbial testing reagents for the classification of positive cytochrome oxidase and aerobic microorganisms. Used as an oxidase reagent.
Last Update:2022-10-16 17:27:35

637-01-4 - Reference Information

EPA chemical substance information information provided by: ofmpeb.epa.gov (external link)
Overview N,N,N',N'-tetramethyl-p-phenylenediamine dihydrochloride, short for TMPD, is an oxidase reagent, can be used to identify Neisseria gonorrhoeae.
Application N,N,N',N'-tetramethyl-p-phenylenediamine dihydrochloride, can be used to identify Neisseria gonorrhoeae. The principle is that Neisseria gonorrhoeae has an oxidase, and the oxygen ions it produces can oxidize the oxidase reagent (N,N,N',N'-tetramethyl-p-phenylenediamine dihydrochloride) into a quinone compound, which causes a color reaction.
biological activity TMPD dihydrozolide, a compound susceptible to oxidation, it is a redox-active substrate molecule for enzymatic conversion. TMPD dihydrochloride is also an electron donor and acts as a reducing co-substrate for heme peroxidase. TMPD dihydrochloride is also a substrate for complex IV.
Last Update:2024-04-09 15:16:52
637-01-4
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Shanghai Macklin Biochemical Co., Ltd
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Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: |N,N,N',N'|-Tetramethyl-|p|-phenylenediamine dihydrochloride (TMPD) Visit Supplier Webpage Request for quotation
CAS: 637-01-4
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Suzhou Haofan biological Co., Ltd.
Featured Products
Product Name: N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride Request for quotation
CAS: 637-01-4
Tel: +86 0512-69209928
Email: wuhao@highfine.com
     merry@highfine.com
     chenmengqi@highfine.com
QQ: 4006286883 Click to send a QQ message
Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: N1,N1,N4,N4-Tetramethylbenzene-1,4-diamine dihydrochloride Request for quotation
CAS: 637-01-4
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: (N,N,N',N')-Tetramethyl-P-phenylenediamine dihydrochloride (TMPD) Visit Supplier Webpage Request for quotation
CAS: 637-01-4
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
MedChemExpress (MCE)
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Product Name: TMPD Visit Supplier Webpage Request for quotation
CAS: 637-01-4
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
Shanghai Yuanye Bio-Technology Co., Ltd.
Spot supply
Product Name: TMPD Visit Supplier Webpage Request for quotation
CAS: 637-01-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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