5472-41-3
4-Amino-6-hydroxypyrazolo[3,4-d]pyrimidine
CAS: 5472-41-3
Molecular Formula: C5H5N5O
5472-41-3 - Names and Identifiers
| Name | 4-Amino-6-hydroxypyrazolo[3,4-d]pyrimidine |
| Synonyms | TIMTEC-BB SBB004064 4-aminopyrazolo(3,4-d)pyrimidin-6-ol 4-Aminopyrazolo[3,4-d]pyrimidine-6-ol 4-Amino-6-hydroxypyrazolo[3,4-d]pyrimidine 4-AMINO-6-hydroxypyrazolo-(3,4-d)pyrimidine 4-Amino-5H-pyrazolo[3,4-d]pyrimidin-6(7H)-one 4-amino-1,2-dihydro-6H-pyrazolo[3,4-d]pyrimidin-6-one 4-Amino-1,5-dihydro-6H-pyrazolo[3,4-d]pyrimidin-6-one |
| CAS | 5472-41-3 |
| EINECS | 226-811-1 |
| InChI | InChI=1/C5H5N5O/c6-3-2-1-7-10-4(2)9-5(11)8-3/h1H,(H4,6,7,8,9,10,11) |
5472-41-3 - Physico-chemical Properties
| Molecular Formula | C5H5N5O |
| Molar Mass | 151.13 |
| Density | 1.4456 (rough estimate) |
| Melting Point | 320 °C |
| Boling Point | 273.11°C (rough estimate) |
| Flash Point | 166.6°C |
| Vapor Presure | 3.98E-05mmHg at 25°C |
| Maximum wavelength(λmax) | ['250nm(H2O)(lit.)'] |
| BRN | 152192 |
| pKa | 4.65±0.40(Predicted) |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.9000 (estimate) |
| MDL | MFCD00005689 |
5472-41-3 - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | 25 - Toxic if swallowed |
| Safety Description | S24/25 - Avoid contact with skin and eyes. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2811 6.1 / PGIII |
| HS Code | 29335995 |
5472-41-3 - Introduction
[3,4-d]pyrimidine is an organic compound with the chemical formula C5H4N4O. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: [3,4-d]pyrimidine is a white to pale yellow crystalline or crystalline powder.
-Melting point: The melting point of the compound is about 210-212°C.
-Solubility: Its solubility in water is low, but it is soluble in some organic solvents such as alcohols and ketones.
-Stability: The compound is relatively stable at room temperature, but should avoid prolonged exposure to the sun.
Use:
-Drug research: [3,4-d]pyrimidine is an important intermediate commonly used in the synthesis of a variety of pharmaceutical compounds.
-Pesticide: It can also be used to synthesize certain fungicides and herbicides.
Preparation Method:
The preparation of [3,4-d]pyrimidine can be carried out by the following steps:
1. Add isocyanate in ice-cold sulfuric acid.
2. Under mild conditions, the reaction product of the previous step is reacted with 5-chloro-6-hydroxypyrazole.
3. The reaction product is reacted with sodium aminocyanide using an alkali catalyst.
4. Finally, the target product was purified by crystallization.
Safety Information:
[3,4-d]pyrimidine specific safety information may vary depending on national and regional requirements. Observe the following general safety practices when handling and using:
-Avoid direct contact with skin and eyes. In case of contact, rinse immediately with plenty of water.
-Wear appropriate protective gloves and goggles during operation.
-Use in a well-ventilated place and avoid inhaling its dust or vapor.
-Dispose of waste and residues according to proper disposal methods.
Please note that this information is for informational purposes only. In practical application, further evaluation and appropriate safety measures should be taken according to the specific situation.
Nature:
-Appearance: [3,4-d]pyrimidine is a white to pale yellow crystalline or crystalline powder.
-Melting point: The melting point of the compound is about 210-212°C.
-Solubility: Its solubility in water is low, but it is soluble in some organic solvents such as alcohols and ketones.
-Stability: The compound is relatively stable at room temperature, but should avoid prolonged exposure to the sun.
Use:
-Drug research: [3,4-d]pyrimidine is an important intermediate commonly used in the synthesis of a variety of pharmaceutical compounds.
-Pesticide: It can also be used to synthesize certain fungicides and herbicides.
Preparation Method:
The preparation of [3,4-d]pyrimidine can be carried out by the following steps:
1. Add isocyanate in ice-cold sulfuric acid.
2. Under mild conditions, the reaction product of the previous step is reacted with 5-chloro-6-hydroxypyrazole.
3. The reaction product is reacted with sodium aminocyanide using an alkali catalyst.
4. Finally, the target product was purified by crystallization.
Safety Information:
[3,4-d]pyrimidine specific safety information may vary depending on national and regional requirements. Observe the following general safety practices when handling and using:
-Avoid direct contact with skin and eyes. In case of contact, rinse immediately with plenty of water.
-Wear appropriate protective gloves and goggles during operation.
-Use in a well-ventilated place and avoid inhaling its dust or vapor.
-Dispose of waste and residues according to proper disposal methods.
Please note that this information is for informational purposes only. In practical application, further evaluation and appropriate safety measures should be taken according to the specific situation.
Last Update：2024-04-09 21:00:56
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Spot supply
Product Name: 4-Amino-1H-pyrazolo[3,4-d]pyrimidin-6-ol Request for quotationCAS: 5472-41-3
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Product Name: 4-Amino-6-Hydroxy-1H-Pyrazolo[3,4-d]Pyrimidine Visit Supplier Webpage Request for quotation
CAS: 5472-41-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 5472-41-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
5472-41-3
LMPK12040009
6358-31-2
215872-46-1
Bromaminic acid
DL-2-METHYLBUTYRYL CHLORIDE
1094-08-2
acid blue 92 (C.I. 13390)
异丙醇锡(IV)
865-48-5
LMPK12040009
6358-31-2
215872-46-1
Bromaminic acid
DL-2-METHYLBUTYRYL CHLORIDE
1094-08-2
acid blue 92 (C.I. 13390)
异丙醇锡(IV)
865-48-5