497883-22-4 - Names and Identifiers
497883-22-4 - Physico-chemical Properties
Molecular Formula | C36H30NO2P
|
Molar Mass | 539.60 |
Melting Point | 102-103°C |
Boling Point | 710.7±63.0 °C(Predicted) |
pKa | -0.57±0.20(Predicted) |
Storage Condition | 2-8℃ |
Use | (11BS)-N,N-bis [(R)-1-phenylethyl]-binaphtho [2,1-D:1 ',2'-F][1,3,2] dioxyphosphine -4-amine is mainly used as an organophosphorus ligand and can be used in laboratory research and development processes and chemical production processes. Chiral phosphoramidite ligands for copper-catalyzed high enantioselective conjugate addition reactions that allow the addition of dialkyl zinc to various Michael receptors. 1,2,3 can also be used for diethylzinc-mediated palladium-catalyzed polarity reversal allylation. |
497883-22-4 - Risk and Safety
497883-22-4 - Introduction
(11bS)-N,N-Bis[(R)-1-phenylethyl]-dinaphtho[2,1-d:1 ',2'-f][1,3,2]dioxaphosphepin-4-amine is an organic compound with the following properties and applications:
Nature:
-Appearance: White to light yellow solid
-Molecular formula: C30H26N2O2P
-Molecular weight: 474.51g/mol
-Melting Point: about 195-205 ℃
-Solubility: Slightly soluble in water, soluble in organic solvents such as chloroform, dichloromethane and ethanol.
Use:
- ((11bS)-N,N-Bis[(R)-1-phenylethyl]-dinaphtho[2,1-d:1 ',2'-f][1,3,2]dioxaphosphepin-4-amine is commonly used as a chiral ligand for catalytic asymmetric catalytic reactions in organic synthesis reactions.
-It can be used in asymmetric nucleophilic addition reaction, asymmetric free radical reaction, asymmetric cyclization reaction and asymmetric reduction reaction.
Method:
((11bS)-N,N-Bis[(R)-1-phenylethyl]-dinaphtho[2,1-d:1 ',2'-f][1,3,2] The preparation method of dioxaphosphepin-4-amine is more complicated, and it can be synthesized by multi-step reaction in the laboratory. A typical method involves the synthesis of an N-phosphonamide Intermediate followed by a BIS-phosphorylation and substitution reaction to obtain the desired product.
Safety Information:
The safety and toxicity information of this compound is relatively limited, so it is necessary to follow laboratory safety procedures when handling, and ensure appropriate protective equipment and measures. In addition, local regulations and guidelines need to be followed for the storage and handling of organic compounds. If necessary, please operate in a professional laboratory or under suitable environmental conditions.
Last Update:2024-04-10 22:29:15