497883-22-4

497883-22-4 - Names and Identifiers

Name	(11bS)-N,N-Bis[(R)-1-phenylethyl]-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine
Synonyms	(11bS)-N,N-Bis[(R)-1-phenylethyl]-dinaphtho[2,1-d
CAS	497883-22-4

497883-22-4 - Physico-chemical Properties

Molecular Formula	C36H30NO2P
Molar Mass	539.60
Melting Point	102-103°C
Boling Point	710.7±63.0 °C(Predicted)
pKa	-0.57±0.20(Predicted)
Storage Condition	2-8℃
Use	(11BS)-N,N-bis [(R)-1-phenylethyl]-binaphtho [2,1-D:1 ',2'-F][1,3,2] dioxyphosphine -4-amine is mainly used as an organophosphorus ligand and can be used in laboratory research and development processes and chemical production processes. Chiral phosphoramidite ligands for copper-catalyzed high enantioselective conjugate addition reactions that allow the addition of dialkyl zinc to various Michael receptors. 1,2,3 can also be used for diethylzinc-mediated palladium-catalyzed polarity reversal allylation.

497883-22-4 - Risk and Safety

WGK Germany

497883-22-4 - Introduction

(11bS)-N,N-Bis[(R)-1-phenylethyl]-dinaphtho[2,1-d:1 ',2'-f][1,3,2]dioxaphosphepin-4-amine is an organic compound with the following properties and applications:

Nature:
-Appearance: White to light yellow solid
-Molecular formula: C30H26N2O2P
-Molecular weight: 474.51g/mol
-Melting Point: about 195-205 ℃
-Solubility: Slightly soluble in water, soluble in organic solvents such as chloroform, dichloromethane and ethanol.

Use:
- ((11bS)-N,N-Bis[(R)-1-phenylethyl]-dinaphtho[2,1-d:1 ',2'-f][1,3,2]dioxaphosphepin-4-amine is commonly used as a chiral ligand for catalytic asymmetric catalytic reactions in organic synthesis reactions.
-It can be used in asymmetric nucleophilic addition reaction, asymmetric free radical reaction, asymmetric cyclization reaction and asymmetric reduction reaction.

Method:
((11bS)-N,N-Bis[(R)-1-phenylethyl]-dinaphtho[2,1-d:1 ',2'-f][1,3,2] The preparation method of dioxaphosphepin-4-amine is more complicated, and it can be synthesized by multi-step reaction in the laboratory. A typical method involves the synthesis of an N-phosphonamide Intermediate followed by a BIS-phosphorylation and substitution reaction to obtain the desired product.

Safety Information:
The safety and toxicity information of this compound is relatively limited, so it is necessary to follow laboratory safety procedures when handling, and ensure appropriate protective equipment and measures. In addition, local regulations and guidelines need to be followed for the storage and handling of organic compounds. If necessary, please operate in a professional laboratory or under suitable environmental conditions.

Last Update：2024-04-10 22:29:15